Abstract
Leishmaniases constitute a group of diseases caused by protozoa of the genus Leishmania, which infect cells of the mononuclear phagocytic system and produce lesions on the skin and mucous membranes (cutaneous and mucocutaneous leishmaniasis) and internal organs (visceral leishmaniasis). Cutaneous and mucocutaneous leishmaniasis causes ulcerated or nodular lesions on the skin and nasal and oral mucous membranes. Visceral leishmaniasis compromises internal organs and is manifested by weight loss, hepatomegaly, splenomegaly, and bone marrow dysfunction, with anemia, neutropenia, and hemorrhages. The lesions of cutaneous leishmaniasis are destructive and progressive, causing aesthetic and functional damage, especially in the facial region: nose and mouth. When left untreated, visceral leishmaniasis is usually lethal; in treated individuals, lethality is around 6%. Leishmaniasis is present on all continents, except Oceania.
| Original language | English |
|---|---|
| Title of host publication | Neglected Zoonoses and Antimicrobial Resistance |
| Subtitle of host publication | Impact on One Health and Sustainable Development Goals |
| Publisher | Elsevier |
| Pages | 87-124 |
| Number of pages | 38 |
| ISBN (Electronic) | 9780443160622 |
| ISBN (Print) | 9780443160639 |
| DOIs | |
| Publication status | Published - 1 Jan 2024 |
Bibliographical note
Publisher Copyright:© 2025 Elsevier Inc. All rights reserved.
Keywords
- Clinical manifestations
- Cutaneous leishmaniasis
- Diagnosis
- Leishmania
- Parasitology
- Protozoa
- Treatment
- Vector borne disease
- Visceral leishmaniasis