TY - JOUR
T1 - Legionnaires' disease outbreak associated with a cruise liner, August 2003
T2 - Epidemiological and microbiological findings
AU - Beyrer, Konrad
AU - Lai, S.
AU - Dreesman, J.
AU - Lee, J. V.
AU - Joseph, C.
AU - Harrison, Timothy
AU - Surman-Lee, S.
AU - Lück, C.
AU - Brodhun, B.
AU - Buchholz, U.
AU - Windorfer, A.
N1 - Copyright:
Copyright 2008 Elsevier B.V., All rights reserved.
PY - 2007/6
Y1 - 2007/6
N2 - Eight cases of Legionnaires' disease were identified among the 215 German passengers after a cruise to the Nordic Sea in August 2003. An unmatched case-control study was conducted to identify risk factors and the source of infection. In total, eight passengers fulfilled the case definition, one of these died. Forty-two passengers served as controls. The attack rate was 4%. The mean age was 60 years for cases and 62 years for controls. Prolonged exposure to the spa pool seemed to be a risk factor of infection (OR 4.85, P=0.09). Legionella pneumophila serogroup 1, monoclonal antibody (mAb) subgroup 'Knoxville' was isolated from clinical and environmental samples. DNA sequence-based typing revealed that these isolates were indistinguishable from each other. The investigation showed the importance of an interdisciplinary approach of microbiology and epidemiology as not all sites on the ship that tested positive for L. pneumophila actually posed a relevant risk for the passengers.
AB - Eight cases of Legionnaires' disease were identified among the 215 German passengers after a cruise to the Nordic Sea in August 2003. An unmatched case-control study was conducted to identify risk factors and the source of infection. In total, eight passengers fulfilled the case definition, one of these died. Forty-two passengers served as controls. The attack rate was 4%. The mean age was 60 years for cases and 62 years for controls. Prolonged exposure to the spa pool seemed to be a risk factor of infection (OR 4.85, P=0.09). Legionella pneumophila serogroup 1, monoclonal antibody (mAb) subgroup 'Knoxville' was isolated from clinical and environmental samples. DNA sequence-based typing revealed that these isolates were indistinguishable from each other. The investigation showed the importance of an interdisciplinary approach of microbiology and epidemiology as not all sites on the ship that tested positive for L. pneumophila actually posed a relevant risk for the passengers.
UR - http://www.scopus.com/inward/record.url?scp=34547436433&partnerID=8YFLogxK
U2 - 10.1017/S0950268806007473
DO - 10.1017/S0950268806007473
M3 - Article
C2 - 17109773
AN - SCOPUS:34547436433
SN - 0950-2688
VL - 135
SP - 802
EP - 810
JO - Epidemiology and Infection
JF - Epidemiology and Infection
IS - 5
ER -
