TY - JOUR
T1 - Investing in health preparedness, response and resilience
T2 - a genomics costing tool focused on next generation sequencing
AU - Akande, Oluwatosin Wuraola
AU - Afrough, Babak
AU - Amante, Maria
AU - Carter, Lisa
AU - Cunningham, Jane
AU - Hull, Noah Clayton
AU - Inamdar, Leena
AU - Jaguparov, Alexandr
AU - Marklewitz, Marco
AU - Musul, Biran
AU - Norberg, Ashley
AU - Pereyaslov, Dmitriy I.
AU - Poates, Angela Lee
AU - Samaan, Gina
AU - Suresh, Anita
AU - Uplekar, Swapna
AU - Wilhem, Aude
AU - Salvi Le Garrec Zwetyenga, Joanna
AU - Whistler, Toni
N1 - Publisher Copyright:
Copyright © 2024 Akande, Afrough, Amante, Carter, Cunningham, Hull, Inamdar, Jaguparov, Marklewitz, Musul, Norberg, Pereyaslov, Poates, Samaan, Suresh, Uplekar, Wilhem, Salvi Le Garrec Zwetyenga and Whistler.
PY - 2024
Y1 - 2024
N2 - The world has seen unprecedented gains in the global genomic surveillance capacities for pathogens with pandemic and epidemic potential within the last 4 years. To strengthen and sustain the gains made, WHO is working with countries and partners to implement the Global Genomic Surveillance Strategy for Pathogens with Pandemic and Epidemic Potential 2022–2032. A key technical product developed through these multi-agency collaborative efforts is a genomics costing tool (GCT), as sought by many countries. This tool was developed by five institutions – Association of Public Health Laboratories, FIND, The Global Fund to Fight AIDS, Tuberculosis and Malaria, UK Health Security Agency, and the World Health Organization. These institutions developed the GCT to support financial planning and budgeting for SARS-CoV-2 next-generation sequencing activities, including bioinformatic analysis. The tool costs infrastructure, consumables and reagents, human resources, facility and quality management. It is being used by countries to (1) obtain costs of routine sequencing and bioinformatics activities, (2) optimize available resources, and (3) build an investment case for the scale-up or establishment of sequencing and bioinformatics activities. The tool has been validated and is available in English and Russian at https://www.who.int/publications/i/item/9789240090866. This paper aims to highlight the rationale for developing the tool, describe the process of the collaborative effort in developing the tool, and describe the utility of the tool to countries.
AB - The world has seen unprecedented gains in the global genomic surveillance capacities for pathogens with pandemic and epidemic potential within the last 4 years. To strengthen and sustain the gains made, WHO is working with countries and partners to implement the Global Genomic Surveillance Strategy for Pathogens with Pandemic and Epidemic Potential 2022–2032. A key technical product developed through these multi-agency collaborative efforts is a genomics costing tool (GCT), as sought by many countries. This tool was developed by five institutions – Association of Public Health Laboratories, FIND, The Global Fund to Fight AIDS, Tuberculosis and Malaria, UK Health Security Agency, and the World Health Organization. These institutions developed the GCT to support financial planning and budgeting for SARS-CoV-2 next-generation sequencing activities, including bioinformatic analysis. The tool costs infrastructure, consumables and reagents, human resources, facility and quality management. It is being used by countries to (1) obtain costs of routine sequencing and bioinformatics activities, (2) optimize available resources, and (3) build an investment case for the scale-up or establishment of sequencing and bioinformatics activities. The tool has been validated and is available in English and Russian at https://www.who.int/publications/i/item/9789240090866. This paper aims to highlight the rationale for developing the tool, describe the process of the collaborative effort in developing the tool, and describe the utility of the tool to countries.
KW - cost-analysis
KW - costing tool
KW - genomic sequencing
KW - genomic surveillance
KW - infectious disease
KW - next-generation sequencing
UR - http://www.scopus.com/inward/record.url?scp=85193855536&partnerID=8YFLogxK
U2 - 10.3389/fpubh.2024.1404243
DO - 10.3389/fpubh.2024.1404243
M3 - Article
C2 - 38784596
AN - SCOPUS:85193855536
SN - 2296-2565
VL - 12
JO - Frontiers in Public Health
JF - Frontiers in Public Health
M1 - 1404243
ER -