Invasive pulmonary aspergillosis with spontaneous resolution and the diagnostic utility of PCR from tissue specimens

William W. Hope; Alan Padwell; Malcolm Guiver; David W. Denning

doi:10.1016/j.jinf.2004.02.008

Invasive pulmonary aspergillosis with spontaneous resolution and the diagnostic utility of PCR from tissue specimens

William W. Hope^*, Alan Padwell, Malcolm Guiver, David W. Denning

^*Corresponding author for this work

Manchester Lab Clinical Development

Research output: Contribution to journal › Article › peer-review

5 Citations (Scopus)

Abstract

This case describes a 61-year-old apparently immunocompetent female with invasive pulmonary aspergillosis (IPA) and eosinophilia who demonstrated spontaneous clinical and radiological recovery. The patient had a history of asthma and had been corticosteroid dependent until 2 months prior to her presentation. This report explores the role of PCR in confirming the diagnosis of invasive aspergillosis in circumstances where only histological data are available and highlights the fact that invasive infections with Aspergillus spp. can occur without profound immunological deficiency. The case also documents the resolution of IPA without specific therapy.

Original language	English
Pages (from-to)	136-140
Number of pages	5
Journal	Journal of Infection
Volume	49
Issue number	2
DOIs	https://doi.org/10.1016/j.jinf.2004.02.008
Publication status	Published - Aug 2004

Keywords

Aspergillosis
Aspergillus
Diagnosis
EORTC/MSG
PCR

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1016/j.jinf.2004.02.008

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title = "Invasive pulmonary aspergillosis with spontaneous resolution and the diagnostic utility of PCR from tissue specimens",

abstract = "This case describes a 61-year-old apparently immunocompetent female with invasive pulmonary aspergillosis (IPA) and eosinophilia who demonstrated spontaneous clinical and radiological recovery. The patient had a history of asthma and had been corticosteroid dependent until 2 months prior to her presentation. This report explores the role of PCR in confirming the diagnosis of invasive aspergillosis in circumstances where only histological data are available and highlights the fact that invasive infections with Aspergillus spp. can occur without profound immunological deficiency. The case also documents the resolution of IPA without specific therapy.",

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AU - Hope, William W.

AU - Padwell, Alan

AU - Guiver, Malcolm

AU - Denning, David W.

PY - 2004/8

Y1 - 2004/8

N2 - This case describes a 61-year-old apparently immunocompetent female with invasive pulmonary aspergillosis (IPA) and eosinophilia who demonstrated spontaneous clinical and radiological recovery. The patient had a history of asthma and had been corticosteroid dependent until 2 months prior to her presentation. This report explores the role of PCR in confirming the diagnosis of invasive aspergillosis in circumstances where only histological data are available and highlights the fact that invasive infections with Aspergillus spp. can occur without profound immunological deficiency. The case also documents the resolution of IPA without specific therapy.

AB - This case describes a 61-year-old apparently immunocompetent female with invasive pulmonary aspergillosis (IPA) and eosinophilia who demonstrated spontaneous clinical and radiological recovery. The patient had a history of asthma and had been corticosteroid dependent until 2 months prior to her presentation. This report explores the role of PCR in confirming the diagnosis of invasive aspergillosis in circumstances where only histological data are available and highlights the fact that invasive infections with Aspergillus spp. can occur without profound immunological deficiency. The case also documents the resolution of IPA without specific therapy.

KW - Aspergillosis

KW - Aspergillus

KW - Diagnosis

KW - EORTC/MSG

KW - PCR

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SN - 0163-4453

VL - 49

SP - 136

EP - 140

JO - Journal of Infection

JF - Journal of Infection

IS - 2

ER -

Invasive pulmonary aspergillosis with spontaneous resolution and the diagnostic utility of PCR from tissue specimens

Abstract

Keywords

UN SDGs

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