Invasive pneumococcal disease and socioeconomic deprivation: A population study from the North East of England

K. E. Chapman*, D. Wilson, Russell Gorton

*Corresponding author for this work

    Research output: Contribution to journalArticlepeer-review

    12 Citations (Scopus)

    Abstract

    Background: Some communicable diseases disproportionately affect poor and vulnerable groups. Invasive pneumococcal disease (IPD) is an important cause of morbidity and mortality; however, the relationship between IPD and deprivation has not been well described. Methods: Population based study assessing the relationship between incidence of IPD and deprivation in the North East of England using data from an enhanced IPD surveillance system and the 2010 Indices of Multiple Deprivation and the Rural and Urban Area Classification. Results: The incidence of IPD increased linearly with increasing deprivation from 7.0 per 100 000 population to 13.6 per 100 000 population. This association was demonstrated for the 16-64 and ≥65 year age groups, but not the <16 year age group. IPD incidence was strongly associated with all individual domains of deprivation except for the 'barriers to housing and services' domain. IPD incidence was higher in urban than rural areas. Conclusions: The risk of IPD is strongly associated with deprivation in adults, but not children. The mechanisms producing the associations observed remain unclear and require further investigation. Findings from this study reinforce the need to address social inequalities to reduce the burden of disease. Targeting vaccination at adults living in deprived areas could reduce the burden of IPD.

    Original languageEnglish
    Pages (from-to)558-569
    Number of pages12
    JournalJournal of Public Health (United Kingdom)
    Volume35
    Issue number4
    DOIs
    Publication statusPublished - Dec 2013

    Bibliographical note

    Funding Information:
    This work was supported by a grant from the Health Protection Agency Strategic Research and Development Fund between April 2009 and March 2012; and an unrestricted educational grant from Sanofi Pasteur MSD (UK12C1036) from April 2012.

    Keywords

    • Communicable diseases
    • Pneumococcal
    • Social determinants
    • Socioeconomics factors

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