Introduction and historical perspective

Keith Alan Foster, Peter Hambleton, Clifford Shone

Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review

1 Citation (Scopus)


Tetanus and botulism are lethal diseases of humans and animals that present as characteristic muscular paralyses consequent upon highly neurological disorders induced by members of the most potent group of acute toxins known. These powerful toxins are produced by the anaerobic, spore-forming bacteria Clostridium tetani and Clostridium botulinum. Although these diseases have been known since antiquity when they were described by both Greeks and Romans, their bacterial origins were only recognized in the late 19th century.

Original languageEnglish
Title of host publicationTreatments from Toxins
Subtitle of host publicationThe Therapeutic Potential of Clostridial Neurotoxins
PublisherCRC Press
Number of pages17
ISBN (Electronic)9781420004151
ISBN (Print)0849327091, 9780849327094
Publication statusPublished - 1 Jan 2006


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