Abstract
National Salmonella surveillance systems from France, England and Wales, Denmark, and the United States identified the recent emergence of multidrug-resistant isolates of Salmonella enterica serotype Kentucky displaying high-level resistance to ciprofloxacin. A total of 489 human cases were identified during the period from 2002 (3 cases) to 2008 (174 cases). These isolates belonged to a single clone defined by the multilocus sequence type ST198, the XbaI-pulsed-field gel electrophoresis cluster X1, and the presence of the Salmonella genomic island 1 variant SGI1-K. This clone was probably selected in 3 steps in Egypt during the 1990s and the early 2000s and has now spread to several countries in Africa and, more recently, in the Middle East. Poultry has been identified as a potential major vehicle for infection by this clone. Continued surveillance and appropriate control measures should be implemented by national and international authorities to limit the spread of this strain.
| Original language | English |
|---|---|
| Pages (from-to) | 675-684 |
| Number of pages | 10 |
| Journal | Journal of Infectious Diseases |
| Volume | 204 |
| Issue number | 5 |
| DOIs | |
| Publication status | Published - 1 Sept 2011 |
Bibliographical note
Funding Information:Permanent financial support came from the institutes, universities, or national agencies of the authors. The work conducted at the National Food Institute, Technical University of Denmark was supported by the World Health Organization Global Foodborne Infections Network (www.who.int/ gfn) and the Danish Research Agency (274-05-0117).
Funding Information:
The MLST data are publicly available at http://mlst.ucc.ie, which is currently funded by a grant from the Science Foundation of Ireland (05/ FE1/B882).
Funding Information:
This work was supported by the Institut Pasteur; the Danish Research Agency (274-05-0117); the World Health Organization Global Foodborne Infections Network; the Institut National de la Recherche Agronomique; the Health Protection Agency; the Statens Serum Institute; the Centers for Disease Control and Prevention; the Institut Pasteur du Maroc; the University of Ibadan; the Agence Franxcaise de Sécurité Sanitaire des Aliments; the Réseau international des Instituts Pasteur et instituts associés; and the Institut de Veille Sanitaire.
