Inequalities in excess premature mortality in England during the COVID-19 pandemic: A cross-sectional analysis of cumulative excess mortality by area deprivation and ethnicity

Sharmani Barnard, Paul Fryers*, Justine Fitzpatrick, Sebastian Fox, Zachary Waller, Allan Baker, Paul Burton, John Newton, Yvonne Doyle, Peter Goldblatt

*Corresponding author for this work

    Research output: Contribution to journalArticlepeer-review

    8 Citations (Scopus)
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    Abstract

    Objectives: To examine magnitude of the impact of the COVID-19 pandemic on inequalities in premature mortality in England by deprivation and ethnicity. 

    Design: A statistical model to estimate increased mortality in population subgroups during the COVID-19 pandemic by comparing observed with expected mortality in each group based on trends over the previous 5 years. 

    Setting: Information on deaths registered in England since 2015 was used, including age, sex, area of residence and cause of death. Ethnicity was obtained from Hospital Episode Statistics records linked to death data. 

    Participants: Population study of England, including all 569 824 deaths from all causes registered between 21 March 2020 and 26 February 2021. 

    Main outcome measures: Excess mortality in each subgroup over and above the number expected based on trends in mortality in that group over the previous 5 years. 

    Results: The gradient in excess mortality by area deprivation was greater in the under 75s (the most deprived areas had 1.25 times as many deaths as expected, least deprived 1.14) than in all ages (most deprived had 1.24 times as many deaths as expected, least deprived 1.20). Among the black and Asian groups, all area deprivation quintiles had significantly larger excesses than white groups in the most deprived quintiles and there were no clear gradients across quintiles. Among the white group, only those in the most deprived quintile had more excess deaths than deaths directly involving COVID-19. 

    Conclusion: The COVID-19 pandemic has widened inequalities in premature mortality by area deprivation. Among those under 75, the direct and indirect effects of the pandemic on deaths have disproportionately impacted ethnic minority groups irrespective of area deprivation, and the white group the most deprived areas. Statistics limited to deaths directly involving COVID-19 understate the pandemic's impact on inequalities by area deprivation and ethnic group at younger ages.

    Original languageEnglish
    Article numbere052646
    JournalBMJ Open
    Volume11
    Issue number12
    Early online date23 Dec 2021
    DOIs
    Publication statusE-pub ahead of print - 23 Dec 2021

    Bibliographical note

    Funding Information: SB acknowledges funding received from the ARC Centre of Excellence for Children and Families over the Life Course (Life Course Centre).

    Open Access: This is an open access article distributed in accordance with the
    Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which
    permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/.

    Publisher Copyright: © Author(s) (or their employer(s)) 2021. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.

    Citation: Barnard S, Fryers P, Fitzpatrick J, et al. Inequalities in excess premature mortality in England during the COVID-19 pandemic: a cross-sectional analysis of cumulative excess mortality by area deprivation and ethnicity. BMJ Open 2021;11:e052646. doi: 10.1136/bmjopen-2021-052646

    DOI: 10.1136/bmjopen-2021-052646

    Keywords

    • COVID-19
    • epidemiology
    • public health

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