We synthesized evidence from the POPI sexual-health cohort study and estimated that 4.9% (95% credible interval, .4–14.1%) of Mycoplasma genitalium infections in women progress to pelvic inflammatory disease versus 14.4% (5.9–24.6%) of chlamydial infections. For validation, we predicted PID rates in 4 age groups that agree well with surveillance data.
Bibliographical noteFunding Information:
J. L. and P. J. W. were supported by the NIHR Health Protection Research Unit (HPRU) in Modelling Methodology at Imperial College London in partnership with PHE (grant number HPRU-2012?10080). P. J. W. was also supported by the MRC Centre for Global Infectious Disease Analysis (grant number MR/R015600/1); this award is jointly funded by the MRC and the Department for International Development (DFID) under the MRC/DFID Concordat agreement and is also part of the European & Developing Countries Clinical Trials Partnership 2 (EDCTP2) program supported by the European Union. P. J. H. was supported by the NIHR HPRU in Evaluation of Interventions at the University of Bristol in partnership with PHE (grant number HPRU-2012?10026).
© The Author(s) 2020.
- Evidence synthesis
- Mycoplasma genitalium
- Pelvic inflammatory disease
- Population attributable fraction