Implementation of a Highly Accurate Rapid Point-of-Care Test for Group a Streptococcus Detection at a Large Pediatric Emergency Department in South London

Alicia Demirjian; Amaya L. Bustinduy; Shamez Ladhani; Yasser Iqbal; Mike Sharland

doi:10.1097/INF.0000000000002284

Implementation of a Highly Accurate Rapid Point-of-Care Test for Group a Streptococcus Detection at a Large Pediatric Emergency Department in South London

Alicia Demirjian^*
, Amaya L. Bustinduy
, Shamez Ladhani
, Yasser Iqbal
, Mike Sharland

^*Corresponding author for this work

Immunisation & Vaccine Preventable Diseases

Research output: Contribution to journal › Article › peer-review

5 Citations (Scopus)

Abstract

Rapid group A Streptococcus point-of-care testing is not currently used in the United Kingdom in the management of acute tonsillitis. This prospective, observational study describes a strong association between a molecular-based point-of-care testing result and outpatient antibiotic prescribing (odds ratio = 48; P < 0.001) in 339 children seen at our center. It highlights challenges in implementing new rapid diagnostics.

Original language	English
Pages (from-to)	E183-E185
Journal	Pediatric Infectious Disease Journal
Volume	38
Issue number	8
DOIs	https://doi.org/10.1097/INF.0000000000002284
Publication status	Published - 1 Aug 2019

Bibliographical note

Publisher Copyright:
© 2019 Wolters Kluwer Health, Inc. All rights reserved.

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

antimicrobial stewardship
diagnostic stewardship
group A Streptococcus
molecular diagnostics
outpatient antibiotic prescribing

Access to Document

10.1097/INF.0000000000002284

Cite this

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title = "Implementation of a Highly Accurate Rapid Point-of-Care Test for Group a Streptococcus Detection at a Large Pediatric Emergency Department in South London",

abstract = "Rapid group A Streptococcus point-of-care testing is not currently used in the United Kingdom in the management of acute tonsillitis. This prospective, observational study describes a strong association between a molecular-based point-of-care testing result and outpatient antibiotic prescribing (odds ratio = 48; P < 0.001) in 339 children seen at our center. It highlights challenges in implementing new rapid diagnostics.",

keywords = "antimicrobial stewardship, diagnostic stewardship, group A Streptococcus, molecular diagnostics, outpatient antibiotic prescribing",

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Implementation of a Highly Accurate Rapid Point-of-Care Test for Group a Streptococcus Detection at a Large Pediatric Emergency Department in South London. / Demirjian, Alicia; Bustinduy, Amaya L.; Ladhani, Shamez et al.
In: Pediatric Infectious Disease Journal, Vol. 38, No. 8, 01.08.2019, p. E183-E185.

Research output: Contribution to journal › Article › peer-review

TY - JOUR

T1 - Implementation of a Highly Accurate Rapid Point-of-Care Test for Group a Streptococcus Detection at a Large Pediatric Emergency Department in South London

AU - Demirjian, Alicia

AU - Bustinduy, Amaya L.

AU - Ladhani, Shamez

AU - Iqbal, Yasser

AU - Sharland, Mike

PY - 2019/8/1

Y1 - 2019/8/1

N2 - Rapid group A Streptococcus point-of-care testing is not currently used in the United Kingdom in the management of acute tonsillitis. This prospective, observational study describes a strong association between a molecular-based point-of-care testing result and outpatient antibiotic prescribing (odds ratio = 48; P < 0.001) in 339 children seen at our center. It highlights challenges in implementing new rapid diagnostics.

AB - Rapid group A Streptococcus point-of-care testing is not currently used in the United Kingdom in the management of acute tonsillitis. This prospective, observational study describes a strong association between a molecular-based point-of-care testing result and outpatient antibiotic prescribing (odds ratio = 48; P < 0.001) in 339 children seen at our center. It highlights challenges in implementing new rapid diagnostics.

KW - antimicrobial stewardship

KW - diagnostic stewardship

KW - group A Streptococcus

KW - molecular diagnostics

KW - outpatient antibiotic prescribing

UR - https://www.scopus.com/pages/publications/85070008626

U2 - 10.1097/INF.0000000000002284

DO - 10.1097/INF.0000000000002284

M3 - Article

C2 - 31310596

AN - SCOPUS:85070008626

SN - 0891-3668

VL - 38

SP - E183-E185

JO - Pediatric Infectious Disease Journal

JF - Pediatric Infectious Disease Journal

IS - 8

ER -

Implementation of a Highly Accurate Rapid Point-of-Care Test for Group a Streptococcus Detection at a Large Pediatric Emergency Department in South London

Abstract

Bibliographical note

UN SDGs

Keywords

Access to Document

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