Impact of infectious diseases consultation on the management of Staphylococcus aureus bacteraemia in children

Rebecca B. Saunderson, Theodore Gouliouris, Edward J. Cartwright, Emma J. Nickerson, Sani H. Aliyu, D. Roddy O'Donnell, Wilf Kelsall, D. Limmathurotsakul, Sharon Peacock, M. Estée Török*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

14 Citations (Scopus)


Objectives: Infectious diseases consultation (IDC) in adults with Staphylococcus aureus bacteraemia (SAB) has been shown to improve management and outcome. The aim of this study was to evaluate the impact of IDC on the management of SAB in children. Study design: Observational cohort study of children with SAB. Setting: Cambridge University Hospitals National Health Service (NHS) Foundation Trust, a large acute NHS Trust in the UK. Participants: All children with SAB admitted to the Cambridge University Hospitals NHS Foundation Trust between 16 July 2006 and 31 December 2012. Methods: Children with SAB between 2006 and 31 October 2009 were managed by routine clinical care (pre-IDC group) and data were collected retrospectively by case notes review. An IDC service for SAB was introduced in November 2009. All children with SAB were reviewed regularly and data were collected prospectively (IDC group) until 31 December 2012. Baseline characteristics, quality metrics and outcome were compared between the pre-IDC group and IDC group. Results: There were 66 episodes of SAB in 63 children - 28 patients (30 episodes) in the pre-IDC group, and 35 patients (36 episodes) in the IDC group. The median age was 3.4 years (IQR 0.2-10.7 years). Patients in the IDC group were more likely to have echocardiography performed, a removable focus of infection identified and to receive a longer course of intravenous antimicrobial therapy. There were no differences in total duration of antibiotic therapy, duration of hospital admission or outcome at 30 or 90 days following onset of SAB. Conclusions: IDC resulted in improvements in the investigation and management of SAB in children.

Original languageEnglish
Article numbere004659
JournalBMJ Open
Issue number7
Publication statusPublished - 2014


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