Human parvoviruses

Maria Söderlund-Venermo, Kevin E. Brown, Dean D. Erdman

Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review

1 Citation (Scopus)


Parvoviruses have been isolated from a wide range of animals, including mammals, birds, insects, crustaceans, and reptiles. These viruses tend to be species-specific and can cause a variety of serious diseases in their host species (1). The first parvoviruses isolated from humans were adeno-associated parvoviruses, which have not yet been linked with disease. Until recently the only parvovirus associated with human disease was human parvovirus B19 (B19V), which was fortuitously identified in 1975 during an evaluation of tests for hepatitis B virus antigens (2). B19V has been associated with erythema infectiosum, transient aplastic crisis, chronic anemia in patients with impaired immune systems, hydrops fetalis, and purportedly a number of other conditions (3). Seven additional parvoviruses have recently been detected in humans by molecular screening for new sequences, including human bocavirus (HBoV)1-4, tetraparvovirus (PARV4), bufavirus (BuV), and tusavirus (TuV) (4-9). HBoV1 causes acute respiratory illness (10) and, as with HBoV2 and 3, possibly also encephalitis (11). The other recently discovered human parvoviruses are yet to be associated with human disease.

Original languageEnglish
Title of host publicationClinical Virology
Number of pages21
ISBN (Electronic)9781683670674
ISBN (Print)9781555819422
Publication statusPublished - 7 Mar 2016

Bibliographical note

Publisher Copyright:
© 2017 by ASM Press.


  • Clinical manifestations
  • Epidemiological differences
  • Human parvoviruses
  • Laboratory diagnosis
  • Physical treatments
  • Virology


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