Human listeriosis in Britain, 1967–85, a summary of 722 cases: 2. Listeriosis in non-pregnant individuals, a changing pattern of infection and seasonal incidence

James McLauchlin*

*Corresponding author for this work

    Research output: Contribution to journalArticlepeer-review

    107 Citations (Scopus)

    Abstract

    Clinical information was collected on 722 cases of Listeria monocytogenes infections in humans occurring in Britain between 1967 and 1985. This series comprised 34% (248 cases) associated with pregnancy and 66% (474 cases) in non-pregnant adults and juveniles. The cases not associated with pregnancy comprised: 76% in patients with severe underlying illness (of which 34% had central nervous system infections, and 42 % bacteraemia without involvement of the central nervous system); 21% in previously healthy individuals (of whom 18% had meningitis); and 3% in patients without bacteraemia or involvement of the central nervous system. Cases occurred most often in male patients over 40 years of age. The overall mortality was 44%. Overall, the pattern of infection has altered to a disease of higher incidence, affecting most often susceptible non-pregnant individuals and the unborn. An annual increase in incidence of listeriosis occurred in the autumn in all categories of patients.

    Original languageEnglish
    Pages (from-to)191-201
    Number of pages11
    JournalEpidemiology and Infection
    Volume104
    Issue number2
    DOIs
    Publication statusPublished - Apr 1990

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