HTLV seroprevalence in people using HIV pre-exposure prophylaxis in England

Daniel Bradshaw*, Arham Khawar, Poorvi Patel, Jennifer Tosswill, Colin Brown, Dana Ogaz, Emily Mason, Roeann Osman, Holly Mitchell, Olamide Dosekun, Borja Mora Peris, Graham Pickard, Michael Rayment, Rachael Jones, Mark Hopkins, Andy Williams, Margaret Kingston, Nicholas Machin, Yusri Taha, Sarah DuncanNeil Turner, Noel Gill, Nick Andrews, Mohammad Raza, Simon Tazzyman, Achyuta Nori, Emma Cunningham, Graham P. Taylor

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

2 Citations (Scopus)


Objectives: HTLV-1 is predominantly a sexually-transmitted infection but testing is not mentioned in HIV-PrEP guidelines. We ascertained HTLV-1/HTLV-2 seroprevalence amongst HIV-PrEP users in England. Methods: An unlinked anonymous seroprevalence study. Results: Amongst 2015 HIV-PrEP users, 95% were men, 76% of white ethnicity and 83% had been born in Europe. There were no HTLV-1/HTLV-2 seropositive cases (95% confidence interval 0% – 0.18%). Conclusions: There were no HTLV positive cases, likely reflecting the demographic of mostly white and European-born individuals. Similar studies are needed worldwide to inform public health recommendations for HIV-PrEP using populations, particularly in HTLV-endemic settings.

Original languageEnglish
Pages (from-to)245-247
Number of pages3
JournalJournal of Infection
Issue number3
Publication statusPublished - Mar 2023

Bibliographical note

Publisher Copyright:
© 2023


  • Bisexual and other men who have sex with men (GBMSM)
  • Gay
  • HIV pre-exposure prophylaxis
  • Human T cell lymphotropic virus type 1 (HTLV-1)


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