Horizontal Gene Transfer Among Neisseria Species and Humans

S. Sánchez; T. de Miguel; T. G. Villa; A. R. Gorringe; I. M. Feavers

doi:10.1007/978-3-030-21862-1_15

Horizontal Gene Transfer Among Neisseria Species and Humans

S. Sánchez^*, T. de Miguel, T. G. Villa, A. R. Gorringe, I. M. Feavers

^*Corresponding author for this work

Research & Development Institute Scientific Leaders

Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

Abstract

The genus Neisseria is included among those organisms containing a large number of foreign or exogenous genes in its genome. In most cases, the incorporation of these foreign genes is the consequence of recent events of horizontal gene transfer (HGT) occurring between different species of Neisseria but also with other bacterial genera such as Haemophilus influenzae and even with its exclusive host, the human. In this chapter, we review the transformation process as the main mechanism of HGT in Neisseria and its role in the acquisition of virulence factors and antibiotic resistance markers, mainly from commensal to pathogen Neisseria spp. In addition, we review evidence of gene exchange between both pathogenic Neisseria spp. and human, showing that HGT can occur between mammal’s host and their associated bacteria.

Original language	English
Title of host publication	Horizontal Gene Transfer
Subtitle of host publication	Breaking Borders between Living Kingdoms
Publisher	Springer International Publishing
Pages	361-376
Number of pages	16
ISBN (Electronic)	9783030218621
ISBN (Print)	9783030218614
DOIs	https://doi.org/10.1007/978-3-030-21862-1_15
Publication status	Published - 1 Jan 2019

Bibliographical note

Publisher Copyright:
© Springer Nature Switzerland AG 2019.

Keywords

Antibiotic resistance
Horizontal gene transfer
Neisseria gonorrhoeae
Neisseria meningitidis
Neisseria spp.
Transformation

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10.1007/978-3-030-21862-1_15

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AU - de Miguel, T.

AU - Villa, T. G.

AU - Gorringe, A. R.

AU - Feavers, I. M.

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Horizontal Gene Transfer Among Neisseria Species and Humans

Abstract

Bibliographical note

Keywords

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