TY - JOUR
T1 - Home outdoor NO2 and new onset of self-reported asthma in adults
AU - Jacquemin, Bénédicte
AU - Sunyer, Jordi
AU - Forsberg, Bertil
AU - Aguilera, Inmaculada
AU - Briggs, David
AU - García-Esteban, Raquel
AU - Götschi, Thomas
AU - Heinrich, Joachim
AU - Järvholm, Bengt
AU - Jarvis, Debbie
AU - Vienneau, Danielle
AU - Künzli, Nino
PY - 2009/1
Y1 - 2009/1
N2 - BACKGROUND: Few studies have investigated new onset of asthma in adults in relation to air pollution. The aim of this study is to investigate the association between modeled background levels of traffic-related air pollution at the subjects' home addresses and self-reported asthma incidence in a European adult population. METHODS: Adults from the European Respiratory Health Survey were included (n = 4185 from 17 cities). Subjects' home addresses were geocoded and linked to outdoor nitrogen dioxide (NO2) estimates, as a marker of local traffic-related pollution. We obtained this information from the 1-km background NO2 surface modeled in APMoSPHERE (Air Pollution Modelling for Support to Policy on Health and Environmental Risk in Europe). Asthma incidence was defined as reporting asthma in the follow-up (1999 to 2001) but not in the baseline (1991 to 1993). RESULTS: A positive association was found between NO2 and asthma incidence (odds ratio 1.43; 95% confidence interval = 1.02 to 2.01) per 10 μg/m. Results were homogeneous among centers (P value for heterogeneity = 0.59). CONCLUSIONS: We found an association between a marker of traffic-related air pollution and asthma incidence in European adults.
AB - BACKGROUND: Few studies have investigated new onset of asthma in adults in relation to air pollution. The aim of this study is to investigate the association between modeled background levels of traffic-related air pollution at the subjects' home addresses and self-reported asthma incidence in a European adult population. METHODS: Adults from the European Respiratory Health Survey were included (n = 4185 from 17 cities). Subjects' home addresses were geocoded and linked to outdoor nitrogen dioxide (NO2) estimates, as a marker of local traffic-related pollution. We obtained this information from the 1-km background NO2 surface modeled in APMoSPHERE (Air Pollution Modelling for Support to Policy on Health and Environmental Risk in Europe). Asthma incidence was defined as reporting asthma in the follow-up (1999 to 2001) but not in the baseline (1991 to 1993). RESULTS: A positive association was found between NO2 and asthma incidence (odds ratio 1.43; 95% confidence interval = 1.02 to 2.01) per 10 μg/m. Results were homogeneous among centers (P value for heterogeneity = 0.59). CONCLUSIONS: We found an association between a marker of traffic-related air pollution and asthma incidence in European adults.
UR - http://www.scopus.com/inward/record.url?scp=66749107835&partnerID=8YFLogxK
U2 - 10.1097/EDE.0b013e3181886e76
DO - 10.1097/EDE.0b013e3181886e76
M3 - Article
C2 - 18923331
AN - SCOPUS:66749107835
SN - 1044-3983
VL - 20
SP - 119
EP - 126
JO - Epidemiology
JF - Epidemiology
IS - 1
ER -
