The proportion of new HIV diagnoses between May and December 2009 across Odessa recently-infected was estimated using the BED-CEIA assay. Logistic regression models were used to explore factors associated with testing as recent. Of 1,313 newly-diagnosed individuals, 321 (24 %) were classified as recent. Recent infection was less likely among older adults [odds ratio (OR) = 0.70 per 10-year increase, 95 % CI 0.60-0.82]. Compared to men residing in Odessa city, women in rural Odessa and non-resident men were more likely to be recently-infected (OR 1.85, 1.26-2.71 and 2.83, 1.15-6.97, respectively). Reason for test was not associated with recent infection. In sensitivity analysis, after excluding individuals tested due to clinical indications, the proportion recently-infected and the association with age remained virtually unchanged. Our findings suggest a high risk of onward transmission, particularly in younger age groups. These findings highlight the need for tailored prevention strategies and ongoing RITA testing to monitor and evaluate effectiveness of prevention programmes.
Bibliographical noteFunding Information:
This study was conducted on behalf of CASCADE Collaboration in EuroCoord. The members of CASCADE Collaboration in EuroCoord are given in Appendix. The research leading to these results has received funding from the European Union Seventh Framework Programme (FP7/2007-2013) under EuroCoord grant agreement n° 260694. Ruth Simmons is funded through a doctoral grant from the Medical Research Council, UK.
The study was part of CASCADE within EuroCoord (www.EuroCoord.net) funded by the European Union Framework Programme VII. Ethics approval was given by the Odessa Province Sanitarium and Epidemiological Station including that additional consent is not required from participants.
- HIV incidence
- Onward transmission