Abstract
Analysis of the nucleotide sequence of a 1592 bp region. of Acetobacter xylinum genomic DNA involved in acetan biosynthesis revealed the presence of an open-reading frame (aceM) encoding a protein of 449 amino acids with a molecular weight of 48.5 kDa. The deduced amino acid sequence of aceM displayed high homology to the protein sequences of genes encoding UDP-glucose dehydrogenase (UGDH) activities from other organisms. AceM is likely to encode the UGDH involved in the biosynthesis of UDP-glucuronic acid required for acetan biosynthesis.
Original language | English |
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Pages (from-to) | 469-474 |
Number of pages | 6 |
Journal | Biotechnology Letters |
Volume | 19 |
Issue number | 5 |
DOIs | |
Publication status | Published - 1997 |
Externally published | Yes |
Bibliographical note
Funding Information:This work was funded by the Biotechnology and Biological Sciences Research Council. The sequence has been deposited in the EMBL databank under the Accession Number Y11203.