Factors affecting adherence to asthma treatment in an international cohort of young and middle-aged adults

Angelo G. Corsico; Lucia Cazzoletti; Roberto de Marco; Christer Janson; Deborah Jarvis; Maria C. Zoia; Massimiliano Bugiani; Simone Accordini; Simona Villani; Alessandra Marinoni; David Gislason; Amund Gulsvik; Isabelle Pin; Paul Vermeire; Isa Cerveri

doi:10.1016/j.rmed.2006.11.012

Factors affecting adherence to asthma treatment in an international cohort of young and middle-aged adults

Angelo G. Corsico^*, Lucia Cazzoletti, Roberto de Marco, Christer Janson, Deborah Jarvis, Maria C. Zoia, Massimiliano Bugiani, Simone Accordini, Simona Villani, Alessandra Marinoni, David Gislason, Amund Gulsvik, Isabelle Pin, Paul Vermeire, Isa Cerveri

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

63 Citations (Scopus)

Abstract

Background: A major reason of the poor control of asthma is that patients fail to adhere to their treatment. The aim of the study was to identify factors affecting changes in asthma treatment adherence in an international cohort. Methods: A follow-up study was carried out by means of a structured clinical interview in 971 subjects with asthma from 12 countries who participated in both the European Community Respiratory Health Survey: ECRHS-I (1990-94) and ECRHS-II (1998-2002). Subjects were considered adherent if they reported they normally took all the prescribed drugs. A logistic model was used to study the adjusted effect of the determinants. Results: The net change in adherence to anti-asthmatic treatment per 10 years of follow-up was -2% (95% CI: -9.5, 5.5), 7.5% (-2.6, 17.6), 15.0% (6.6, 23.5) and 19.8% (4.1, 35.5), respectively, in Nordic, Mediterranean, Continental and extra-European areas. Among the 428 non-adherent subjects in ECRHS-I, having regular consultations with health care professionals was the strongest predictor of increased adherence (OR 3.32; 95% CI: 1.08-10.17). Among the 543 adherent subjects in ECRHS-I, using inhaled corticosteroids significantly predicted a persistence of adherence (OR 2.04; 95% CI: 1.11-3.75). No effect of gender, age, duration of the disease, smoking habit and educational level was observed. Conclusions: Our findings highlight the key role of doctors and nurses in educating and regularly reviewing the patients and support the efforts for an improvement of clinical communication.

Original language	English
Pages (from-to)	1363-1367
Number of pages	5
Journal	Respiratory Medicine
Volume	101
Issue number	6
DOIs	https://doi.org/10.1016/j.rmed.2006.11.012
Publication status	Published - Jun 2007
Externally published	Yes

Bibliographical note

Funding Information:
The coordination of ECRHS-II was supported by the European Commission, as part of their Quality of Life program. The Pavia center was supported by Ricerca Corrente 80149/RCR 1998 IRCCS Policlinico San Matteo. Funding for the other individual centers is listed at: ⟨www.ecrhs.org⟩ .

Keywords

Education
Epidemiology
Guideline
Health beliefs

Access to Document

10.1016/j.rmed.2006.11.012

Cite this

Corsico, A. G., Cazzoletti, L., de Marco, R., Janson, C., Jarvis, D., Zoia, M. C., Bugiani, M., Accordini, S., Villani, S., Marinoni, A., Gislason, D., Gulsvik, A., Pin, I., Vermeire, P., & Cerveri, I. (2007). Factors affecting adherence to asthma treatment in an international cohort of young and middle-aged adults. Respiratory Medicine, 101(6), 1363-1367. https://doi.org/10.1016/j.rmed.2006.11.012

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title = "Factors affecting adherence to asthma treatment in an international cohort of young and middle-aged adults",

abstract = "Background: A major reason of the poor control of asthma is that patients fail to adhere to their treatment. The aim of the study was to identify factors affecting changes in asthma treatment adherence in an international cohort. Methods: A follow-up study was carried out by means of a structured clinical interview in 971 subjects with asthma from 12 countries who participated in both the European Community Respiratory Health Survey: ECRHS-I (1990-94) and ECRHS-II (1998-2002). Subjects were considered adherent if they reported they normally took all the prescribed drugs. A logistic model was used to study the adjusted effect of the determinants. Results: The net change in adherence to anti-asthmatic treatment per 10 years of follow-up was -2% (95% CI: -9.5, 5.5), 7.5% (-2.6, 17.6), 15.0% (6.6, 23.5) and 19.8% (4.1, 35.5), respectively, in Nordic, Mediterranean, Continental and extra-European areas. Among the 428 non-adherent subjects in ECRHS-I, having regular consultations with health care professionals was the strongest predictor of increased adherence (OR 3.32; 95% CI: 1.08-10.17). Among the 543 adherent subjects in ECRHS-I, using inhaled corticosteroids significantly predicted a persistence of adherence (OR 2.04; 95% CI: 1.11-3.75). No effect of gender, age, duration of the disease, smoking habit and educational level was observed. Conclusions: Our findings highlight the key role of doctors and nurses in educating and regularly reviewing the patients and support the efforts for an improvement of clinical communication.",

keywords = "Education, Epidemiology, Guideline, Health beliefs",

author = "Corsico, {Angelo G.} and Lucia Cazzoletti and {de Marco}, Roberto and Christer Janson and Deborah Jarvis and Zoia, {Maria C.} and Massimiliano Bugiani and Simone Accordini and Simona Villani and Alessandra Marinoni and David Gislason and Amund Gulsvik and Isabelle Pin and Paul Vermeire and Isa Cerveri",

note = "Funding Information: The coordination of ECRHS-II was supported by the European Commission, as part of their Quality of Life program. The Pavia center was supported by Ricerca Corrente 80149/RCR 1998 IRCCS Policlinico San Matteo. Funding for the other individual centers is listed at: ⟨www.ecrhs.org⟩ . ",

year = "2007",

month = jun,

doi = "10.1016/j.rmed.2006.11.012",

language = "English",

volume = "101",

pages = "1363--1367",

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Corsico, AG, Cazzoletti, L, de Marco, R, Janson, C, Jarvis, D, Zoia, MC, Bugiani, M, Accordini, S, Villani, S, Marinoni, A, Gislason, D, Gulsvik, A, Pin, I, Vermeire, P & Cerveri, I 2007, 'Factors affecting adherence to asthma treatment in an international cohort of young and middle-aged adults', Respiratory Medicine, vol. 101, no. 6, pp. 1363-1367. https://doi.org/10.1016/j.rmed.2006.11.012

TY - JOUR

T1 - Factors affecting adherence to asthma treatment in an international cohort of young and middle-aged adults

AU - Corsico, Angelo G.

AU - Cazzoletti, Lucia

AU - de Marco, Roberto

AU - Janson, Christer

AU - Jarvis, Deborah

AU - Zoia, Maria C.

AU - Bugiani, Massimiliano

AU - Accordini, Simone

AU - Villani, Simona

AU - Marinoni, Alessandra

AU - Gislason, David

AU - Gulsvik, Amund

AU - Pin, Isabelle

AU - Vermeire, Paul

AU - Cerveri, Isa

N1 - Funding Information: The coordination of ECRHS-II was supported by the European Commission, as part of their Quality of Life program. The Pavia center was supported by Ricerca Corrente 80149/RCR 1998 IRCCS Policlinico San Matteo. Funding for the other individual centers is listed at: ⟨www.ecrhs.org⟩ .

PY - 2007/6

Y1 - 2007/6

N2 - Background: A major reason of the poor control of asthma is that patients fail to adhere to their treatment. The aim of the study was to identify factors affecting changes in asthma treatment adherence in an international cohort. Methods: A follow-up study was carried out by means of a structured clinical interview in 971 subjects with asthma from 12 countries who participated in both the European Community Respiratory Health Survey: ECRHS-I (1990-94) and ECRHS-II (1998-2002). Subjects were considered adherent if they reported they normally took all the prescribed drugs. A logistic model was used to study the adjusted effect of the determinants. Results: The net change in adherence to anti-asthmatic treatment per 10 years of follow-up was -2% (95% CI: -9.5, 5.5), 7.5% (-2.6, 17.6), 15.0% (6.6, 23.5) and 19.8% (4.1, 35.5), respectively, in Nordic, Mediterranean, Continental and extra-European areas. Among the 428 non-adherent subjects in ECRHS-I, having regular consultations with health care professionals was the strongest predictor of increased adherence (OR 3.32; 95% CI: 1.08-10.17). Among the 543 adherent subjects in ECRHS-I, using inhaled corticosteroids significantly predicted a persistence of adherence (OR 2.04; 95% CI: 1.11-3.75). No effect of gender, age, duration of the disease, smoking habit and educational level was observed. Conclusions: Our findings highlight the key role of doctors and nurses in educating and regularly reviewing the patients and support the efforts for an improvement of clinical communication.

AB - Background: A major reason of the poor control of asthma is that patients fail to adhere to their treatment. The aim of the study was to identify factors affecting changes in asthma treatment adherence in an international cohort. Methods: A follow-up study was carried out by means of a structured clinical interview in 971 subjects with asthma from 12 countries who participated in both the European Community Respiratory Health Survey: ECRHS-I (1990-94) and ECRHS-II (1998-2002). Subjects were considered adherent if they reported they normally took all the prescribed drugs. A logistic model was used to study the adjusted effect of the determinants. Results: The net change in adherence to anti-asthmatic treatment per 10 years of follow-up was -2% (95% CI: -9.5, 5.5), 7.5% (-2.6, 17.6), 15.0% (6.6, 23.5) and 19.8% (4.1, 35.5), respectively, in Nordic, Mediterranean, Continental and extra-European areas. Among the 428 non-adherent subjects in ECRHS-I, having regular consultations with health care professionals was the strongest predictor of increased adherence (OR 3.32; 95% CI: 1.08-10.17). Among the 543 adherent subjects in ECRHS-I, using inhaled corticosteroids significantly predicted a persistence of adherence (OR 2.04; 95% CI: 1.11-3.75). No effect of gender, age, duration of the disease, smoking habit and educational level was observed. Conclusions: Our findings highlight the key role of doctors and nurses in educating and regularly reviewing the patients and support the efforts for an improvement of clinical communication.

KW - Education

KW - Epidemiology

KW - Guideline

KW - Health beliefs

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DO - 10.1016/j.rmed.2006.11.012

M3 - Article

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SN - 0954-6111

VL - 101

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EP - 1367

JO - Respiratory Medicine

JF - Respiratory Medicine

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ER -

Factors affecting adherence to asthma treatment in an international cohort of young and middle-aged adults

Abstract

Bibliographical note

Keywords

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