TY - JOUR
T1 - Estimating mixed field effects
T2 - An application supporting the lack of a non-linear component for chromosome aberration induction by neutrons
AU - Ballarini, F.
AU - Biaggi, M.
AU - Edwards, Alan
AU - Ferrari, A.
AU - Ottolenghi, A.
AU - Pelliccioni, M.
AU - Scannicchio, D.
N1 - Copyright:
Copyright 2020 Elsevier B.V., All rights reserved.
PY - 2003
Y1 - 2003
N2 - The action of neutron fields on biological structures was investigated on the basis of chromosome aberration induction in human cells. Available experimental data on aberration induction by neutrons and their interaction products were reviewed. Present criteria adopted in neutron radiation protection were discussed. The linear coefficient α and the quadratic coefficient β describing dose-response curves for dicentric chromosomes induced by neutrons of different energies were calculated via integration of experimental data on dicentric induction by photons and charged particles into the Monte Carlo transport code FLUKA. The predicted values of the linear coefficients for neutron beams of different energies showed good agreement with the corresponding experimental values, whereas the data themselves indicated that the neutron quadratic coefficient cannot be obtained by 'averaging' the β values of recoil ions and other nuclear reaction products. This supports the hypothesis that neutron induced aberrations increase substantially linearly with dose, a question that has been object of debate for a long time and is still open.
AB - The action of neutron fields on biological structures was investigated on the basis of chromosome aberration induction in human cells. Available experimental data on aberration induction by neutrons and their interaction products were reviewed. Present criteria adopted in neutron radiation protection were discussed. The linear coefficient α and the quadratic coefficient β describing dose-response curves for dicentric chromosomes induced by neutrons of different energies were calculated via integration of experimental data on dicentric induction by photons and charged particles into the Monte Carlo transport code FLUKA. The predicted values of the linear coefficients for neutron beams of different energies showed good agreement with the corresponding experimental values, whereas the data themselves indicated that the neutron quadratic coefficient cannot be obtained by 'averaging' the β values of recoil ions and other nuclear reaction products. This supports the hypothesis that neutron induced aberrations increase substantially linearly with dose, a question that has been object of debate for a long time and is still open.
UR - http://www.scopus.com/inward/record.url?scp=0037239343&partnerID=8YFLogxK
U2 - 10.1093/oxfordjournals.rpd.a006109
DO - 10.1093/oxfordjournals.rpd.a006109
M3 - Article
C2 - 12596985
AN - SCOPUS:0037239343
SN - 0144-8420
VL - 103
SP - 19
EP - 28
JO - Radiation Protection Dosimetry
JF - Radiation Protection Dosimetry
IS - 1
ER -