TY - JOUR
T1 - Epidemiology of mycobacterium bovis disease in humans in England, Wales, and Northern Ireland, 2002–2014
AU - Davidson, Jennifer A.
AU - Loutet, Miranda G.
AU - O’Connor, Catherine
AU - Kearns, Cathriona
AU - Smith, Robert M.M.
AU - Lalor, Maeve
AU - Thomas, Helen
AU - Abubakar, Ibrahim
AU - Zenner, Dominik
N1 - Publisher Copyright:
© 2017, Centers for Disease Control and Prevention (CDC). All rights reserved.
PY - 2017/3
Y1 - 2017/3
N2 - Despite control efforts, Mycobacterium bovis incidence among cattle remains high in parts of England, Wales, and Northern Ireland, attracting political and public health interest in potential spread from animals to humans. To determine incidence among humans and to identify associated factors, we conducted a retrospective cohort analysis of human M. bovis cases in England, Wales, and Northern Ireland during 2002-2014. We identified 357 cases and observed increased annual case numbers (from 17 to 35) and rates. Most patients were ≥65 years of age and born in the United Kingdom. The median age of UK-born patients decreased over time. For 74% of patients, exposure to risk factors accounting for M. bovis acquisition, most frequently consumption of unpasteurized milk, was known. Despite the small increase in case numbers and reduction in patient age, M. bovis infection of humans in England, Wales, and Northern Ireland remains rare.
AB - Despite control efforts, Mycobacterium bovis incidence among cattle remains high in parts of England, Wales, and Northern Ireland, attracting political and public health interest in potential spread from animals to humans. To determine incidence among humans and to identify associated factors, we conducted a retrospective cohort analysis of human M. bovis cases in England, Wales, and Northern Ireland during 2002-2014. We identified 357 cases and observed increased annual case numbers (from 17 to 35) and rates. Most patients were ≥65 years of age and born in the United Kingdom. The median age of UK-born patients decreased over time. For 74% of patients, exposure to risk factors accounting for M. bovis acquisition, most frequently consumption of unpasteurized milk, was known. Despite the small increase in case numbers and reduction in patient age, M. bovis infection of humans in England, Wales, and Northern Ireland remains rare.
UR - http://www.scopus.com/inward/record.url?scp=85013249527&partnerID=8YFLogxK
U2 - 10.3201/eid2303.161408
DO - 10.3201/eid2303.161408
M3 - Article
C2 - 28220748
AN - SCOPUS:85013249527
SN - 1080-6040
VL - 23
SP - 377
EP - 386
JO - Emerging Infectious Diseases
JF - Emerging Infectious Diseases
IS - 3
ER -
