TY - JOUR
T1 - Epidemiology of invasive Haemophilus influenzae disease, Europe, 2007–2014
AU - French Research Group on Epidemiology of Human Spongiform Encephalopathies
AU - European Centre for Disease Prevention and Control Country Experts for Invasive Haemophilus influenzae Disease
AU - Whittaker, Robert
AU - Economopoulou, Assimoula
AU - Dias, Joana Gomes
AU - Bancroft, Elizabeth
AU - Ramliden, Miriam
AU - Celentano, Lucia Pastore
AU - Steindl, Georg
AU - Martiny, Delphine
AU - Grammens, Tine
AU - Georgieva, Teodora
AU - Maikanti-Charalampous, Panayiota
AU - Koliou, Maria
AU - Lebedova, Vera
AU - Krizova, Pavla
AU - Dalby, Tine
AU - Valentiner-Branth, Palle
AU - Epstein, Jevgenia
AU - Kerbo, Natalia
AU - Toropainen, Maija
AU - Kuusi, Markku
AU - Georges, Scarlett
AU - Lepoutre, Agnès
AU - Takla, Anja
AU - Lam, Thien Tri
AU - Georgakopoulou, Theano
AU - Tzanakaki, Georgina
AU - Molnár, Zsuzsanna
AU - Gudnason, Thorolfur
AU - Hardardottir, Hjordis
AU - O’Lorcain, Piaras
AU - Meyler, Kenneth
AU - D’Ancona, Fortunato
AU - Cerquetti, Marina
AU - Savrasova, Larisa
AU - Galajeva, Jelena
AU - Gargasienė, Greta
AU - Caruana, Paul
AU - Melillo, Tanya
AU - Mollema, Liesbeth
AU - Spanjaard, Lodewijk
AU - Steinbakk, Martin
AU - Paradowska-Stankiewicz, Iwona
AU - Kuch, Alicja
AU - Sousa Pinto, Cátia
AU - Lavado, Paula
AU - Stanescu, Aurora
AU - Cristina Giuca, Mihaela
AU - Novakova, Elena
AU - Kastrin, Tamara
AU - Ladhani, Shamez
N1 - Publisher Copyright:
© 2017, Centers for Disease Control and Prevention (CDC). All rights reserved.
PY - 2017/3
Y1 - 2017/3
N2 - We describe the epidemiology of invasive Haemophilus influenzae disease during 2007-2014 in 12 European countries and assess overall H. influenzae disease trends by serotype and patient age. Mean annual notification rate was 0.6 cases/100,000 population, with an increasing annual trend of 3.3% (95% CI 2.3% to 4.3%). The notification rate was highest for patients <1 month of age (23.4 cases/100,000 population). Nontypeable H. influenzae (NTHi) caused 78% of all cases and showed increasing trends among persons <1 month and ≥20 years of age. Serotype f cases showed an increasing trend among persons ≥60 years of age. Serotype b cases showed decreasing trends among persons 1-5 months, 1-4 years, and ≥40 years of age. Sustained success of routine H. influenzae serotype b vaccination is evident. Surveillance systems must adopt a broad focus for invasive H. influenzae disease. Increasing reports of NTHi, particularly among neonates, highlight the potential benefit of a vaccine against NTHi.
AB - We describe the epidemiology of invasive Haemophilus influenzae disease during 2007-2014 in 12 European countries and assess overall H. influenzae disease trends by serotype and patient age. Mean annual notification rate was 0.6 cases/100,000 population, with an increasing annual trend of 3.3% (95% CI 2.3% to 4.3%). The notification rate was highest for patients <1 month of age (23.4 cases/100,000 population). Nontypeable H. influenzae (NTHi) caused 78% of all cases and showed increasing trends among persons <1 month and ≥20 years of age. Serotype f cases showed an increasing trend among persons ≥60 years of age. Serotype b cases showed decreasing trends among persons 1-5 months, 1-4 years, and ≥40 years of age. Sustained success of routine H. influenzae serotype b vaccination is evident. Surveillance systems must adopt a broad focus for invasive H. influenzae disease. Increasing reports of NTHi, particularly among neonates, highlight the potential benefit of a vaccine against NTHi.
UR - https://www.scopus.com/pages/publications/85013278378
U2 - 10.3201/eid2303.161552
DO - 10.3201/eid2303.161552
M3 - Article
C2 - 28220749
AN - SCOPUS:85013278378
SN - 1080-6040
VL - 23
SP - 396
EP - 404
JO - Emerging Infectious Diseases
JF - Emerging Infectious Diseases
IS - 3
ER -
