Epidemiological survey of Clostridium difficile ribotypes in the North East of England during an 18-month period

J. Vanek; K. Hill; J. Collins; A. Berrington; J. Perry; Thomas Inns; Russell Gorton; J. Magee; A. Sails; A. Mullan; F. K. Gould

doi:10.1016/j.jhin.2012.04.017

Epidemiological survey of Clostridium difficile ribotypes in the North East of England during an 18-month period

J. Vanek, K. Hill, J. Collins, A. Berrington^*, J. Perry, Thomas Inns, Russell Gorton, J. Magee, A. Sails, A. Mullan, F. K. Gould

^*Corresponding author for this work

Public Health England

Research output: Contribution to journal › Article › peer-review

12 Citations (Scopus)

Abstract

During an 18-month period, 1606 stool specimens from laboratory-confirmed cases of . Clostridium difficile infection in the North East of England were ribotyped using unrestricted polymerase chain reaction. Of these, 87.6% grew . C. difficile on culture; 70% had one of 10 recognizable ribotypes of which 001, 106 and 027 were the most prevalent. The proportions of ribotypes 002 and 015 declined during the study period, whereas ribotypes 016 and 023 increased. Ribotype 005 was significantly more numerous in males and ribotype 027 was associated with significantly higher mean age. Our findings differ from national data derived from more selective testing.

Original language	English
Pages (from-to)	209-212
Number of pages	4
Journal	Journal of Hospital Infection
Volume	81
Issue number	3
DOIs	https://doi.org/10.1016/j.jhin.2012.04.017
Publication status	Published - Jul 2012

Bibliographical note

Funding Information:
Supported by the North East Strategic Health Authority .

Copyright:
Copyright 2013 Elsevier B.V., All rights reserved.

Keywords

Clostridium difficile infection
Ribotypes

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Access to Document

10.1016/j.jhin.2012.04.017

Cite this

@article{3c873620a80a4835b4cd76b07bf5aa6e,

title = "Epidemiological survey of Clostridium difficile ribotypes in the North East of England during an 18-month period",

abstract = "During an 18-month period, 1606 stool specimens from laboratory-confirmed cases of . Clostridium difficile infection in the North East of England were ribotyped using unrestricted polymerase chain reaction. Of these, 87.6% grew . C. difficile on culture; 70% had one of 10 recognizable ribotypes of which 001, 106 and 027 were the most prevalent. The proportions of ribotypes 002 and 015 declined during the study period, whereas ribotypes 016 and 023 increased. Ribotype 005 was significantly more numerous in males and ribotype 027 was associated with significantly higher mean age. Our findings differ from national data derived from more selective testing.",

keywords = "Clostridium difficile infection, Ribotypes",

author = "J. Vanek and K. Hill and J. Collins and A. Berrington and J. Perry and Thomas Inns and Russell Gorton and J. Magee and A. Sails and A. Mullan and Gould, {F. K.}",

year = "2012",

month = jul,

doi = "10.1016/j.jhin.2012.04.017",

language = "English",

volume = "81",

pages = "209--212",

journal = "Journal of Hospital Infection",

issn = "0195-6701",

publisher = "Elsevier",

number = "3",

}

TY - JOUR

T1 - Epidemiological survey of Clostridium difficile ribotypes in the North East of England during an 18-month period

AU - Vanek, J.

AU - Hill, K.

AU - Collins, J.

AU - Berrington, A.

AU - Perry, J.

AU - Inns, Thomas

AU - Gorton, Russell

AU - Magee, J.

AU - Sails, A.

AU - Mullan, A.

AU - Gould, F. K.

PY - 2012/7

Y1 - 2012/7

N2 - During an 18-month period, 1606 stool specimens from laboratory-confirmed cases of . Clostridium difficile infection in the North East of England were ribotyped using unrestricted polymerase chain reaction. Of these, 87.6% grew . C. difficile on culture; 70% had one of 10 recognizable ribotypes of which 001, 106 and 027 were the most prevalent. The proportions of ribotypes 002 and 015 declined during the study period, whereas ribotypes 016 and 023 increased. Ribotype 005 was significantly more numerous in males and ribotype 027 was associated with significantly higher mean age. Our findings differ from national data derived from more selective testing.

AB - During an 18-month period, 1606 stool specimens from laboratory-confirmed cases of . Clostridium difficile infection in the North East of England were ribotyped using unrestricted polymerase chain reaction. Of these, 87.6% grew . C. difficile on culture; 70% had one of 10 recognizable ribotypes of which 001, 106 and 027 were the most prevalent. The proportions of ribotypes 002 and 015 declined during the study period, whereas ribotypes 016 and 023 increased. Ribotype 005 was significantly more numerous in males and ribotype 027 was associated with significantly higher mean age. Our findings differ from national data derived from more selective testing.

KW - Clostridium difficile infection

KW - Ribotypes

UR - http://www.scopus.com/inward/record.url?scp=84862651859&partnerID=8YFLogxK

U2 - 10.1016/j.jhin.2012.04.017

DO - 10.1016/j.jhin.2012.04.017

M3 - Article

C2 - 22633277

AN - SCOPUS:84862651859

SN - 0195-6701

VL - 81

SP - 209

EP - 212

JO - Journal of Hospital Infection

JF - Journal of Hospital Infection

IS - 3

ER -

Epidemiological survey of Clostridium difficile ribotypes in the North East of England during an 18-month period

Abstract

Bibliographical note

Keywords

UN SDGs

Access to Document

Other files and links

Fingerprint

Cite this