Abstract
We report the molecular investigations of a large influenza A(H3N2) outbreak, in a season characterised by sharp increase in influenza admissions since December 2016. Analysis of haemagglutinin (HA) sequences demonstrated co-circulation of multiple clades (3C.3a, 3C.2a and 3C.2a1). Most variants fell into a novel subclade (proposed as 3C.2a2); they possessed four unique amino acid substitutions in the HA protein and loss of a potential glycosylation site. These changes potentially modify the H3N2 strain antigenicity.
Original language | English |
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Journal | Eurosurveillance |
Volume | 22 |
Issue number | 8 |
DOIs | |
Publication status | Published - 23 Feb 2017 |
Externally published | Yes |
Bibliographical note
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