Ebola virus persistence in breast milk after no reported illness: A likely source of virus transmission from mother to child

Daouda Sissoko; Mory Keïta; Boubacar Diallo; Negar Aliabadi; David L. Fitter; Benjamin A. Dahl; Joseph Akoi Bore; Fara Raymond Koundouno; Katrin Singethan; Sarah Meisel; Theresa Enkirch; Antonio Mazzarelli; Victoria Amburgey; Ousmane Faye; Amadou Alpha Sall; N'faly Magassouba; Miles W. Carroll; Xavier Anglaret; Denis Malvy; Pierre Formenty; Raymond Bruce Aylward; Sakoba Keïta; Mamoudou Harouna Djingarey; Nicholas J. Loman; Stephan Günther; Sophie Duraffour

doi:10.1093/cid/ciw793

Ebola virus persistence in breast milk after no reported illness: A likely source of virus transmission from mother to child

Daouda Sissoko, Mory Keïta, Boubacar Diallo, Negar Aliabadi, David L. Fitter, Benjamin A. Dahl, Joseph Akoi Bore, Fara Raymond Koundouno, Katrin Singethan, Sarah Meisel, Theresa Enkirch, Antonio Mazzarelli, Victoria Amburgey, Ousmane Faye, Amadou Alpha Sall, N'faly Magassouba, Miles W. Carroll, Xavier Anglaret, Denis Malvy, Pierre FormentyRaymond Bruce Aylward, Sakoba Keïta, Mamoudou Harouna Djingarey, Nicholas J. Loman, Stephan Günther, Sophie Duraffour^*

^*Corresponding author for this work

Research & Development Institute Divisional Office

Research output: Contribution to journal › Article › peer-review

77 Citations (Scopus)

Abstract

A 9-month-old infant died from Ebola virus (EBOV) disease with unknown epidemiological link. While her parents did not report previous illness, laboratory investigations revealed persisting EBOV RNA in the mother's breast milk and the father's seminal fluid. Genomic analysis strongly suggests EBOV transmission to the child through breastfeeding.

Original language	English
Pages (from-to)	513-516
Number of pages	4
Journal	Clinical Infectious Diseases
Volume	64
Issue number	4
DOIs	https://doi.org/10.1093/cid/ciw793
Publication status	Published - 15 Feb 2017

Bibliographical note

Publisher Copyright:
© The Author 2017. Published by Oxford University Press for the Infectious Diseases Society of America.

Keywords

Asymptomatic carriage
Breast milk
Ebola virus
Mother-to-child transmission
Real-time sequencing

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1093/cid/ciw793

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Sissoko, D., Keïta, M., Diallo, B., Aliabadi, N., Fitter, D. L., Dahl, B. A., Bore, J. A., Koundouno, F. R., Singethan, K., Meisel, S., Enkirch, T., Mazzarelli, A., Amburgey, V., Faye, O., Sall, A. A., Magassouba, N., Carroll, M. W., Anglaret, X., Malvy, D., ... Duraffour, S. (2017). Ebola virus persistence in breast milk after no reported illness: A likely source of virus transmission from mother to child. Clinical Infectious Diseases, 64(4), 513-516. https://doi.org/10.1093/cid/ciw793

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title = "Ebola virus persistence in breast milk after no reported illness: A likely source of virus transmission from mother to child",

abstract = "A 9-month-old infant died from Ebola virus (EBOV) disease with unknown epidemiological link. While her parents did not report previous illness, laboratory investigations revealed persisting EBOV RNA in the mother's breast milk and the father's seminal fluid. Genomic analysis strongly suggests EBOV transmission to the child through breastfeeding.",

keywords = "Asymptomatic carriage, Breast milk, Ebola virus, Mother-to-child transmission, Real-time sequencing",

author = "Daouda Sissoko and Mory Ke{\"i}ta and Boubacar Diallo and Negar Aliabadi and Fitter, {David L.} and Dahl, {Benjamin A.} and Bore, {Joseph Akoi} and Koundouno, {Fara Raymond} and Katrin Singethan and Sarah Meisel and Theresa Enkirch and Antonio Mazzarelli and Victoria Amburgey and Ousmane Faye and Sall, {Amadou Alpha} and N'faly Magassouba and Carroll, {Miles W.} and Xavier Anglaret and Denis Malvy and Pierre Formenty and Aylward, {Raymond Bruce} and Sakoba Ke{\"i}ta and Djingarey, {Mamoudou Harouna} and Loman, {Nicholas J.} and Stephan G{\"u}nther and Sophie Duraffour",

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Sissoko, D, Keïta, M, Diallo, B, Aliabadi, N, Fitter, DL, Dahl, BA, Bore, JA, Koundouno, FR, Singethan, K, Meisel, S, Enkirch, T, Mazzarelli, A, Amburgey, V, Faye, O, Sall, AA, Magassouba, N, Carroll, MW, Anglaret, X, Malvy, D, Formenty, P, Aylward, RB, Keïta, S, Djingarey, MH, Loman, NJ, Günther, S & Duraffour, S 2017, 'Ebola virus persistence in breast milk after no reported illness: A likely source of virus transmission from mother to child', Clinical Infectious Diseases, vol. 64, no. 4, pp. 513-516. https://doi.org/10.1093/cid/ciw793

TY - JOUR

T1 - Ebola virus persistence in breast milk after no reported illness

T2 - A likely source of virus transmission from mother to child

AU - Sissoko, Daouda

AU - Keïta, Mory

AU - Diallo, Boubacar

AU - Aliabadi, Negar

AU - Fitter, David L.

AU - Dahl, Benjamin A.

AU - Bore, Joseph Akoi

AU - Koundouno, Fara Raymond

AU - Singethan, Katrin

AU - Meisel, Sarah

AU - Enkirch, Theresa

AU - Mazzarelli, Antonio

AU - Amburgey, Victoria

AU - Faye, Ousmane

AU - Sall, Amadou Alpha

AU - Magassouba, N'faly

AU - Carroll, Miles W.

AU - Anglaret, Xavier

AU - Malvy, Denis

AU - Formenty, Pierre

AU - Aylward, Raymond Bruce

AU - Keïta, Sakoba

AU - Djingarey, Mamoudou Harouna

AU - Loman, Nicholas J.

AU - Günther, Stephan

AU - Duraffour, Sophie

PY - 2017/2/15

Y1 - 2017/2/15

N2 - A 9-month-old infant died from Ebola virus (EBOV) disease with unknown epidemiological link. While her parents did not report previous illness, laboratory investigations revealed persisting EBOV RNA in the mother's breast milk and the father's seminal fluid. Genomic analysis strongly suggests EBOV transmission to the child through breastfeeding.

AB - A 9-month-old infant died from Ebola virus (EBOV) disease with unknown epidemiological link. While her parents did not report previous illness, laboratory investigations revealed persisting EBOV RNA in the mother's breast milk and the father's seminal fluid. Genomic analysis strongly suggests EBOV transmission to the child through breastfeeding.

KW - Asymptomatic carriage

KW - Breast milk

KW - Ebola virus

KW - Mother-to-child transmission

KW - Real-time sequencing

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U2 - 10.1093/cid/ciw793

DO - 10.1093/cid/ciw793

M3 - Article

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AN - SCOPUS:85015834059

SN - 1058-4838

VL - 64

SP - 513

EP - 516

JO - Clinical Infectious Diseases

JF - Clinical Infectious Diseases

IS - 4

ER -

Ebola virus persistence in breast milk after no reported illness: A likely source of virus transmission from mother to child

Abstract

Bibliographical note

Keywords

UN SDGs

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