Ebola virus persistence in breast milk after no reported illness: A likely source of virus transmission from mother to child

Daouda Sissoko, Mory Keïta, Boubacar Diallo, Negar Aliabadi, David L. Fitter, Benjamin A. Dahl, Joseph Akoi Bore, Fara Raymond Koundouno, Katrin Singethan, Sarah Meisel, Theresa Enkirch, Antonio Mazzarelli, Victoria Amburgey, Ousmane Faye, Amadou Alpha Sall, N'faly Magassouba, Miles W. Carroll, Xavier Anglaret, Denis Malvy, Pierre FormentyRaymond Bruce Aylward, Sakoba Keïta, Mamoudou Harouna Djingarey, Nicholas J. Loman, Stephan Günther, Sophie Duraffour*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

72 Citations (Scopus)

Abstract

A 9-month-old infant died from Ebola virus (EBOV) disease with unknown epidemiological link. While her parents did not report previous illness, laboratory investigations revealed persisting EBOV RNA in the mother's breast milk and the father's seminal fluid. Genomic analysis strongly suggests EBOV transmission to the child through breastfeeding.

Original languageEnglish
Pages (from-to)513-516
Number of pages4
JournalClinical Infectious Diseases
Volume64
Issue number4
DOIs
Publication statusPublished - 15 Feb 2017

Bibliographical note

Publisher Copyright:
© The Author 2017. Published by Oxford University Press for the Infectious Diseases Society of America.

Keywords

  • Asymptomatic carriage
  • Breast milk
  • Ebola virus
  • Mother-to-child transmission
  • Real-time sequencing

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