Early experience with the Occlutech PLD occluder for mitral paravalvar leak closure through a hybrid transapical approach

Radwa Bedair, Gareth J. Morgan, Vinayak Bapat, Stamatis Kapetanakis, Sebastian Goreczny, John Simpson, Shakeel A. Qureshi*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

10 Citations (Scopus)


Aims: We sought to evaluate the feasibility and efficacy of hybrid transapical closure of paravalvar mitral leaks using a new Occlutech PLD occluder in patients with heart failure and/or haemolytic anaemia. Methods and results: Retrospective analysis of clinical and procedural data was undertaken for patients who had attempted closure of paravalvar mitral leaks via a hybrid transapical approach with the Occlutech PLD occluder. Eight patients (four males, median age 69 years) underwent closure of 10 mitral paravalvar leaks using eight Occlutech PLD occluders and two AMPLATZER Vascular Plugs (AVP II). Successful deployment, with significant reduction of the paravalvar leak was achieved in seven patients with short procedure (median 131 min) and fluoroscopy times (median 22 min). One patient had mechanical interference with prosthetic valve function, requiring surgery. Another patient with a high EuroSCORE (48.8%) died of multi-organ failure two days after the procedure. Clinical improvement in either heart failure or haemolysis was seen in all discharged patients. Conclusions: In our series of patients with challenging anatomy, the Occlutech PLD occluders performed well when implanted via a hybrid transapical approach. Further work is needed to assess this methodology fully for a wider population and to assess other deployment approaches for this promising new occluder.

Original languageEnglish
Pages (from-to)e1420-e1427
Issue number11
Publication statusPublished - Dec 2016
Externally publishedYes

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© Europa Digital & Publishing 2016. All rights reserved.


  • Hybrid transapical approach
  • Occlutech PLD occluder
  • Paravalvar leak closure


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