TY - JOUR
T1 - Diverse sequence types of Klebsiella pneumoniae contribute to the dissemination of bla NDM-1 in India, Sweden, and the United Kingdom
AU - Giske, Christian G.
AU - Fröding, Inga
AU - Hasan, Chowdhury Mehedi
AU - Turlej-Rogacka, Agata
AU - Toleman, Mark
AU - Livermore, David
AU - Woodford, Neil
AU - Walsh, Timothy R.
PY - 2012/5
Y1 - 2012/5
N2 - Clinical isolates of Klebsiella pneumoniae producing NDM-1 carbapenemase from India (n = 22), the United Kingdom (n = 13), and Sweden (n = 4) were subjected to multilocus sequence typing (MLST), automated repetitive sequence-based PCR (rep-PCR), serotyping, virulence gene screening, and plasmid replicon typing. The most frequently detected MLST sequence types (STs) were ST14 (n = 13; all serotype K2), ST11, ST149, ST231, and ST147. The correlation between MLST and automated rep-PCR was excellent. IncA/C was the most frequently detected plasmid replicon type (n = 14). ST14, ST11, and other successful clones may be important for the dissemination of bla NDM-1.
AB - Clinical isolates of Klebsiella pneumoniae producing NDM-1 carbapenemase from India (n = 22), the United Kingdom (n = 13), and Sweden (n = 4) were subjected to multilocus sequence typing (MLST), automated repetitive sequence-based PCR (rep-PCR), serotyping, virulence gene screening, and plasmid replicon typing. The most frequently detected MLST sequence types (STs) were ST14 (n = 13; all serotype K2), ST11, ST149, ST231, and ST147. The correlation between MLST and automated rep-PCR was excellent. IncA/C was the most frequently detected plasmid replicon type (n = 14). ST14, ST11, and other successful clones may be important for the dissemination of bla NDM-1.
UR - https://www.scopus.com/pages/publications/84860146519
U2 - 10.1128/AAC.06142-11
DO - 10.1128/AAC.06142-11
M3 - Article
C2 - 22354295
AN - SCOPUS:84860146519
SN - 0066-4804
VL - 56
SP - 2735
EP - 2738
JO - Antimicrobial Agents and Chemotherapy
JF - Antimicrobial Agents and Chemotherapy
IS - 5
ER -
