Discovery of hantavirus circulating among Rattus rattus in French Mayotte island, Indian Ocean

Claudia Filippone, Guillaume Castel, Séverine Murri, Frédérik Beaulieux, Myriam Ermonval, Corinne Jallet, Emma L. Wise, Richard J. Ellis, Denise A. Marston, Lorraine M. McElhinney, Anthony R. Fooks, Amélie Desvars, Lénaïg Halos, Gwenaël Vourc’H, Philippe Marianneau, Noël Tordo*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

9 Citations (Scopus)

Abstract

Hantaviruses are emerging zoonotic viruses that cause human diseases. In this study, sera from 642 mammals from La Réunion and Mayotte islands (Indian Ocean) were screened for the presence of hantaviruses by molecular analysis. None of the mammals from La Réunion island was positive, but hantavirus genomic RNA was discovered in 29/160 (18 %) Rattus rattus from Mayotte island. The nucleoprotein coding region was sequenced from the liver and spleen of all positive individuals allowing epidemiological and intra-strain variability analyses. Phylogenetic analysis based on complete coding genomic sequences showed that this Murinae-associated hantavirus is a new variant of Thailand virus. Further studies are needed to investigate hantaviruses in rodent hosts and in Haemorrhagic Fever with Renal Syndrome (HFRS) human cases.

Original languageEnglish
Article number000440
Pages (from-to)1060-1065
Number of pages6
JournalJournal of General Virology
Volume97
Issue number5
DOIs
Publication statusPublished - May 2016
Externally publishedYes

Bibliographical note

Publisher Copyright:
© 2016 The Authors.

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