Direct Measurement of Porto-systemic Gradient in a Failing Fontan Circulation

Madhavi Velpula, Nick Sheron, Neill Guha, Tony Salmon, Nigel Hacking, Gruschen R. Veldtman*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

18 Citations (Scopus)

Abstract

We describe the case history of a 42-year-old man with cardiac cirrhosis, portal hypertension, and life-threatening variceal bleeding after Fontan revision surgery. Direct pressure measurements in the portal vein, though high, demonstrated only a modest portosystemic gradient (PSG), 9mmHg. A transjugular intrahepatic portosystemic shunt procedure was performed. This reduced the PSG (3mmHg). His bleeding was controlled. The patient's histopathological findings were identical to that previously documented in Fontan patients, raising the question of whether these subdiaphragmatic hemodynamics are representative of the broader failing Fontan population.

Original languageEnglish
Pages (from-to)175-178
Number of pages4
JournalCongenital Heart Disease
Volume6
Issue number2
DOIs
Publication statusPublished - Mar 2011
Externally publishedYes

Keywords

  • Cardiac Cirrhosis
  • Fontan Circulation
  • Portal Hypertension
  • Transjugular Intrahepatic Portosystemic Shunt

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