Difficult cases for chromosomal dosimetry: Statistical considerations

Volodymyr A. Vinnikov*, Elizabeth Ainsbury, David Lloyd, Nataliya A. Maznyk, Kai Rothkamm

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

5 Citations (Scopus)

Abstract

Several examples are selected from the literature in order to illustrate combinations of complicating factors, which may occur in real-life radiation exposure scenarios that affect the accuracy of cytogenetic dose estimates. An analysis of limitations in the current statistical methods used in biodosimetry was carried out. Possible directions for further improvement of the statistical basis of chromosomal dosimetry by specific mathematical procedures are outlined.

Original languageEnglish
Pages (from-to)1004-1008
Number of pages5
JournalRadiation Measurements
Volume46
Issue number9
DOIs
Publication statusPublished - Sep 2011

Bibliographical note

Funding Information:
This work has been carried out as part of an International Joint Project JP080153 awarded by the Royal Society of the UK. This support was provided solely for authors' meetings to discuss the data included in the present work. The Royal Society did not influence or participate in study design; in the collection, analysis, and interpretation of data; in the writing of the report; or in the decision to submit the paper for publication.

Keywords

  • Biodosimetry
  • Cytogenetics
  • Data treatment
  • Scenarios of radiation exposure
  • Statistical uncertainty

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