Abstract
Matching individuals reported to a sentinel surveillance scheme for hepatitis C between 2000 and 2005 to individuals with a hospital episode for hepatitis C-related liver disease in the same hospitals, we estimated that the number of cases of hepatitis C-related end-stage liver disease in these English hospitals was 42% (597/419) higher than Hospital Episode Statistics (HES) would indicate. Further, matching records of hepatitis C-related deaths in HES to death certificates, we estimated that, between 2000 and 2005, the true number of deaths from hepatitis C-related end-stage liver disease was between 185% (353/124) and 257% (378/106) higher than the number recorded in routine mortality statistics. We provide estimates of under-recording that can be used to modify existing models of disease burden due to hepatitis C and provide a simple approach to improve the monitoring of trends in severe hepatitis C-related morbidity over time.
Original language | English |
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Pages (from-to) | 513-518 |
Number of pages | 6 |
Journal | Epidemiology and Infection |
Volume | 137 |
Issue number | 4 |
DOIs | |
Publication status | Published - 2009 |
Keywords
- England
- Hepatitis C
- Hepatocellular carcinoma
- Liver cirrhosis