Abstract
We describe detection in the United Kingdom (UK) of the drug-resistant Neisseria gonorrhoeae FC428 clone, with ceftriaxone resistance and intermediate azithromycin resistance. Two female patients developed infection following contact with UK-resident men from the same sexual network linked to travel to Ibiza, Spain. One case failed treatment with ceftriaxone, and azithromycin and gentamicin, before successful treatment with ertapenem. Both isolates had indistinguishable whole-genome sequences. Urgent action is essential to contain this drug-resistant strain.
| Original language | English |
|---|---|
| Article number | 1900147 |
| Journal | Eurosurveillance |
| Volume | 24 |
| Issue number | 10 |
| DOIs | |
| Publication status | Published - 7 Mar 2019 |
Bibliographical note
Funding Information:This work was supported by the National Institute for Health Research Oxford Biomedical Research Centre and the Health Protection Research Unit (NIHR HPRU) in Healthcare Associated Infections and Antimicrobial Resistance at the University of Oxford in partnership with Public Health England (PHE) [HPRU-2012-10041]. DWE is a Big Data Institute Robertson Fellow.
Funding Information:
This work was supported by the National Institute for Health Research Oxford Biomedical Research Centre and the Health Protection Research Unit (NIHR HPRU) in Healthcare Associated Infections and Antimicrobial Resistance at the University of Oxford in partnership with Public Health England (PHE) [HPRU-2012-10041]. DWE is a Big Data Institute Robertson Fellow. We acknowledge the contribution of several unlisted authors, whose names have been withheld to preserve patient confidentially. We would also like to acknowledge Magnus Unemo, Daniel Golparian and Béatrice Berçot for providing sequencing data from previously published studies.
Publisher Copyright:
© 2019, European Centre for Disease Prevention and Control (ECDC). All rights reserved.
