TY - JOUR
T1 - Design and Implementation of a National SARS-CoV-2 Monitoring Program in England
T2 - REACT-1 Study
AU - Elliott, Paul
AU - Whitaker, Matthew
AU - Tang, David
AU - Eales, Oliver
AU - Steyn, Nicholas
AU - Bodinier, Barbara
AU - Wang, Haowei
AU - Elliott, Joshua
AU - Atchison, Christina
AU - Ashby, Deborah
AU - Barclay, Wendy
AU - Taylor, Graham
AU - Darzi, Ara
AU - Cooke, Graham S.
AU - Ward, Helen
AU - Donnelly, Christl A.
AU - Riley, Steven
AU - Chadeau-Hyam, Marc
N1 - Publisher Copyright:
© 2023 American Public Health Association Inc.. All rights reserved.
PY - 2023/5
Y1 - 2023/5
N2 - Data System. The REal-time Assessment of Community Transmission-1 (REACT-1) Study was funded by the Department of Health and Social Care in England to provide reliable and timely estimates of prevalence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection over time, by person and place. Data Collection/Processing. The study team (researchers from Imperial College London and its logistics partner Ipsos) wrote to named individuals aged 5 years and older in random cross-sections of the population of England, using the National Health Service list of patients registered with a general practitioner (near-universal coverage) as a sampling frame. We collected data over 2 to 3 weeks approximately every month across 19 rounds of data collection from May 1, 2020, to March 31, 2022. Data Analysis/Dissemination. We have disseminated the data and study materials widely via the study Web site, preprints, publications in peer-reviewed journals, and the media. We make available data tabulations, suitably anonymized to protect participant confidentiality, on request to the study’s data access committee. Public Health Implications. The study provided inter alia real-time data on SARS-CoV-2 prevalence over time, by area, and by sociodemographic variables; estimates of vaccine effectiveness; and symptom profiles, and detected emergence of new variants based on viral genome sequencing.
AB - Data System. The REal-time Assessment of Community Transmission-1 (REACT-1) Study was funded by the Department of Health and Social Care in England to provide reliable and timely estimates of prevalence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection over time, by person and place. Data Collection/Processing. The study team (researchers from Imperial College London and its logistics partner Ipsos) wrote to named individuals aged 5 years and older in random cross-sections of the population of England, using the National Health Service list of patients registered with a general practitioner (near-universal coverage) as a sampling frame. We collected data over 2 to 3 weeks approximately every month across 19 rounds of data collection from May 1, 2020, to March 31, 2022. Data Analysis/Dissemination. We have disseminated the data and study materials widely via the study Web site, preprints, publications in peer-reviewed journals, and the media. We make available data tabulations, suitably anonymized to protect participant confidentiality, on request to the study’s data access committee. Public Health Implications. The study provided inter alia real-time data on SARS-CoV-2 prevalence over time, by area, and by sociodemographic variables; estimates of vaccine effectiveness; and symptom profiles, and detected emergence of new variants based on viral genome sequencing.
UR - https://www.scopus.com/pages/publications/85152168279
U2 - 10.2105/AJPH.2023.307230
DO - 10.2105/AJPH.2023.307230
M3 - Article
C2 - 36893367
AN - SCOPUS:85152168279
SN - 0090-0036
VL - 113
SP - 545
EP - 554
JO - American Journal of Public Health
JF - American Journal of Public Health
IS - 5
ER -
