Deposition and clearance of inhaled particles in the human nasal passage

M. D. Dorrian*, J. R.H. Smith, M. J. Youngman, M. R. Bailey, G. Etherington, A. L. Shutt

*Corresponding author for this work

Research output: Contribution to journalConference articlepeer-review


Particle deposition in, and clearance from, the human nasal passage investigations are under way and will last for three years. Monodisperse particles ranging from 0.6 to greater than 30 μm are inhaled under three different breathing regimes; sitting and light exercise as defined in ICRP Publication 66, and controlled breathing. Deposition in the nasal passages are measured and clearance followed up for several days from the end of a single acute inhalation. Nose blow samples will be measured to study the assumption in ICRP Publication 66 that all clearance from the anterior region of the nose is intrinsic. Furthermore, the extent of inter-subject variation will be determined.

Original languageEnglish
Pages (from-to)S481
JournalJournal of Aerosol Science
Issue numberSuppl 1
Publication statusPublished - 1996
EventProceedings of the 1996 European Aerosol Conference - Delft, Neth
Duration: 9 Sep 199612 Sep 1996

Bibliographical note

Funding Information:
This work was partiallysupportedby the CEC under contract FI3P-CT920064a.


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