Convalescent plasma therapy for persistent hepatitis E virus infection

Michael Ankcorn*, Jennifer Gallacher, Samreen Ijaz, Yusri Taha, Heli Harvala, Sheila Maclennan, Emma C. Thomson, Chris Davis, Joshua B. Singer, Ana da Silva Filipe, Katherine Smollett, Marc Niebel, Malcolm G. Semple, Richard S. Tedder, Stuart McPherson

*Corresponding author for this work

    Research output: Contribution to journalLetterpeer-review

    16 Citations (Scopus)
    Original languageEnglish
    Pages (from-to)434-438
    Number of pages5
    JournalJournal of Hepatology
    Volume71
    Issue number2
    DOIs
    Publication statusPublished - Aug 2019

    Bibliographical note

    Funding Information:
    Additional virology including HEV-Ag neutralisation work and Illumina whole genome sequencing was funded by NHS Blood and Transplant .

    Funding Information:
    Additional virology including HEV-Ag neutralisation work and Illumina whole genome sequencing was funded by NHS Blood and Transplant. The authors would to thank John Poh, Becky Haywood, Keerthana Jegatheesan, Justin Shute and Steve Dicks in the blood borne virus unit (BBVU), PHE Colindale team for diagnostic work and phylogenetics analysis. We are also grateful for and thank David Williams (PHE, London) and Sreenu Vattipally (CVR, Glasgow) for assistance with using programmes for analysis of short read viral sequences (Illumina). We would like to thank the NHSBT HEV Convalescent Plasma Group which was chaired by Dr Heli Harvala and included Dr Sheila MacLennan, Dr Rekha Anand, Alison Sivyer, Belinda Pelle and Susan Mahenny. Further thanks are extended to Kate Tettmar at the National Transfusion Microbiology Reference Laboratory (NTMRL), NHSBT, Colindale for helping co-ordinate transfer of samples from NTMRL to BBVU.

    Keywords

    • Convalescent plasma
    • Hepatitis E virus
    • Immunocompromised
    • Therapeutics

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