Convalescent plasma for COVID-19: Male gender, older age and hospitalisation associated with high neutralising antibody levels, England, 22 April to 12 May 2020

Jennifer Mehew, Rachel Johnson, David Roberts, Heli Harvala*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

19 Citations (Scopus)

Abstract

We analysed factors associated with neutralising antibody levels in 330 convalescent plasma donors. Women and younger donors were more likely not to have measurable neutralising antibodies, while higher antibody levels were observed in men, in older donors and in those who had been hospitalised. These data will be of value in the timely recruitment of convalescent plasma donors most likely to have high levels of neutralising antibodies for ongoing studies investigating its effectiveness.

Original languageEnglish
Article number2001754
JournalEurosurveillance
Volume25
Issue number45
DOIs
Publication statusPublished - Nov 2020
Externally publishedYes

Bibliographical note

Funding Information:
We would like to acknowledge NHS Blood and Transplant convalescent plasma teams, and those involved in the process from collection to manufacturing and supply into hospitals.

Publisher Copyright:
© 2020 European Centre for Disease Prevention and Control (ECDC). All rights reserved.

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