Consistent high prevalence of undiagnosed blood-borne virus infection in patients attending large urban emergency departments in England

Mark J. Hopkins; Stacy Todd; Mike Beadsworth; Charlotte Anderson; Zameer Mohamed; David Muir; Roberto Vivancos; Ashley S. Brown; Murad Ruf; Anu Chawla

doi:10.1111/jvh.13197

Consistent high prevalence of undiagnosed blood-borne virus infection in patients attending large urban emergency departments in England

Mark J. Hopkins^*, Stacy Todd, Mike Beadsworth, Charlotte Anderson, Zameer Mohamed, David Muir, Roberto Vivancos, Ashley S. Brown, Murad Ruf, Anu Chawla

^*Corresponding author for this work

Field Epidemiology (North West)

Research output: Contribution to journal › Article › peer-review

14 Citations (Scopus)

28 Downloads (Pure)

Abstract

Understanding local viral hepatitis and HIV epidemiology is essential if WHO elimination targets are to be achieved. We demonstrate a consistently high prevalence of undiagnosed active infection in urban emergency department attendees in England, with variations in local risk groups crucial to informing targeted testing initiatives.

Original language	English
Pages (from-to)	88-91
Number of pages	4
Journal	Journal of Viral Hepatitis
Volume	27
Issue number	1
DOIs	https://doi.org/10.1111/jvh.13197
Publication status	Published - 26 Aug 2019

Bibliographical note

Funding Information: This project has been supported through an Association of the British Pharmaceutical Industry (ABPI) ‘Joint Working' initiative with Gilead Sciences. Gilead provided technical expertize, project management and funding for BBV testing. National Health Service (NHS) and Public Health England (PHE) partners contributed independent expertize and skills in their own professional capacity without additional financial support. Data generation and analysis were done independently by NHS and PHE partners. Content, conclusions and recommendations were agreed by consensus by the authors. These are the authors own agreed views and do not necessarily reflect those of their employers.

MJH has received speaker honoraria from Hologic. ZM is the beneficiary of a Gilead HIV/Hepatitis Fellowship. RV is involved in a project to evaluate the impact of rotavirus vaccination funded by GSK. ASB has received research funding from, acted as an investigator for, sat on advisory boards for, and/or received speaker honoraria from the following: Abbvie, Gilead, MSD. MR is an employee of Gilead Sciences. ST, MB, CA, D.M, AC report no potential conflict of interest.

Open Access: This is an open access article under the terms of the Creative Commons Attribution‐NonCommercial‐NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.

Publisher Copyright: © The Authors. Journal of Viral Hepatitis published by John Wiley & Sons Ltd

Citation: Hopkins, MJ, Todd, S, Beadsworth, M, et al. Consistent high prevalence of undiagnosed blood-borne virus infection in patients attending large urban emergency departments in England. J Viral Hepat. 2020; 27: 88– 91.

DOI: https://doi.org/10.1111/jvh.13197

Keywords

emergency department
hepatitis B virus
hepatitis C virus
high prevalence
screening

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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Hopkins2019ConsistentHighPrevalenceOfUndiagnosedBlood-BorneVirusJViralHepatFinal published version, 287 KBLicence: CC BY-NC-ND

Cite this

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title = "Consistent high prevalence of undiagnosed blood-borne virus infection in patients attending large urban emergency departments in England",

abstract = "Understanding local viral hepatitis and HIV epidemiology is essential if WHO elimination targets are to be achieved. We demonstrate a consistently high prevalence of undiagnosed active infection in urban emergency department attendees in England, with variations in local risk groups crucial to informing targeted testing initiatives.",

keywords = "emergency department, hepatitis B virus, hepatitis C virus, high prevalence, screening",

author = "Hopkins, {Mark J.} and Stacy Todd and Mike Beadsworth and Charlotte Anderson and Zameer Mohamed and David Muir and Roberto Vivancos and Brown, {Ashley S.} and Murad Ruf and Anu Chawla",

note = "Funding Information: This project has been supported through an Association of the British Pharmaceutical Industry (ABPI) {\textquoteleft}Joint Working' initiative with Gilead Sciences. Gilead provided technical expertize, project management and funding for BBV testing. National Health Service (NHS) and Public Health England (PHE) partners contributed independent expertize and skills in their own professional capacity without additional financial support. Data generation and analysis were done independently by NHS and PHE partners. Content, conclusions and recommendations were agreed by consensus by the authors. These are the authors own agreed views and do not necessarily reflect those of their employers. MJH has received speaker honoraria from Hologic. ZM is the beneficiary of a Gilead HIV/Hepatitis Fellowship. RV is involved in a project to evaluate the impact of rotavirus vaccination funded by GSK. ASB has received research funding from, acted as an investigator for, sat on advisory boards for, and/or received speaker honoraria from the following: Abbvie, Gilead, MSD. MR is an employee of Gilead Sciences. ST, MB, CA, D.M, AC report no potential conflict of interest. Open Access: This is an open access article under the terms of the Creative Commons Attribution‐NonCommercial‐NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made. Publisher Copyright: {\textcopyright} The Authors. Journal of Viral Hepatitis published by John Wiley & Sons Ltd Citation: Hopkins, MJ, Todd, S, Beadsworth, M, et al. Consistent high prevalence of undiagnosed blood-borne virus infection in patients attending large urban emergency departments in England. J Viral Hepat. 2020; 27: 88– 91. DOI: https://doi.org/10.1111/jvh.13197",

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Consistent high prevalence of undiagnosed blood-borne virus infection in patients attending large urban emergency departments in England

Abstract

Bibliographical note

Keywords

UN SDGs

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