Comparison between biokinetics of inhaled plutonium nitrate and gadolinium oxide in humans and animals

N. Stradling*, George Etherington, Alan Hodgson, Michael Bailey, S. Hodgson, P. Pellow, A. L. Shutt, A. Birchall, E. Rance, D. Newton, K. Fifield

*Corresponding author for this work

    Research output: Contribution to journalArticlepeer-review

    7 Citations (Scopus)


    Due to the paucity of human data after inhalation of different chemical forms of radionuclides, the implications for human exposure are often based on animal studies. This paper describes biokinetic studies of plutonium nitrate and gadolinium oxide in human volunteers and rats. The results, together with information from other studies with radionuclides, suggests that animal studies can be used with advantage for assessing the biokinetic behavior in humans, and for providing guidance on the assessment of intake and optimal monitoring regimens.

    Original languageEnglish
    Pages (from-to)315-325
    Number of pages11
    JournalJournal of Radioanalytical and Nuclear Chemistry Articles
    Issue number2
    Publication statusPublished - 2002

    Bibliographical note

    Funding Information:
    This paper is based on research carried out under the auspices of the Nuclear Fission Safety Programme of the European Commission, Fourth Framework Programme, Contract F14P-CT95-0026. We are also indebted to the Nuclear Installations Inspectorate, Health and Safety Executive, UK, for their financial support for the human volunteer studies. Contract NUC 56/383/1P1E2.


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