Clostridium botulinum toxins: Nature and preparation for clinical use

J. Melling; P. Hambleton; C. C. Shone

doi:10.1038/eye.1988.5

Clostridium botulinum toxins: Nature and preparation for clinical use

J. Melling^*
, P. Hambleton
, C. C. Shone

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

100 Citations (Scopus)

Abstract

C. botulinum neurotoxins are acutely toxic materials and act by inhibiting release of the neurotransmitter acetylcholine. The specific nature of this inhibition is discussed and the preparation and purification of Type A toxin specifically for clinical use is described.

Original language	English
Pages (from-to)	16-23
Number of pages	8
Journal	Eye (Basingstoke)
Volume	2
Issue number	1
DOIs	https://doi.org/10.1038/eye.1988.5
Publication status	Published - Jan 1988

Bibliographical note

Copyright:
Copyright 2016 Elsevier B.V., All rights reserved.

Access to Document

10.1038/eye.1988.5

Cite this

@article{f7d22e62a5f446d88b2374bd7ea502a4,

title = "Clostridium botulinum toxins: Nature and preparation for clinical use",

abstract = "C. botulinum neurotoxins are acutely toxic materials and act by inhibiting release of the neurotransmitter acetylcholine. The specific nature of this inhibition is discussed and the preparation and purification of Type A toxin specifically for clinical use is described.",

author = "J. Melling and P. Hambleton and Shone, \{C. C.\}",

year = "1988",

month = jan,

doi = "10.1038/eye.1988.5",

language = "English",

volume = "2",

pages = "16--23",

journal = "Eye (Basingstoke)",

issn = "0950-222X",

publisher = "Springer Nature",

number = "1",

}

TY - JOUR

T1 - Clostridium botulinum toxins

T2 - Nature and preparation for clinical use

AU - Melling, J.

AU - Hambleton, P.

AU - Shone, C. C.

PY - 1988/1

Y1 - 1988/1

N2 - C. botulinum neurotoxins are acutely toxic materials and act by inhibiting release of the neurotransmitter acetylcholine. The specific nature of this inhibition is discussed and the preparation and purification of Type A toxin specifically for clinical use is described.

AB - C. botulinum neurotoxins are acutely toxic materials and act by inhibiting release of the neurotransmitter acetylcholine. The specific nature of this inhibition is discussed and the preparation and purification of Type A toxin specifically for clinical use is described.

UR - https://www.scopus.com/pages/publications/0023847899

U2 - 10.1038/eye.1988.5

DO - 10.1038/eye.1988.5

M3 - Article

C2 - 3410136

AN - SCOPUS:0023847899

SN - 0950-222X

VL - 2

SP - 16

EP - 23

JO - Eye (Basingstoke)

JF - Eye (Basingstoke)

IS - 1

ER -

Clostridium botulinum toxins: Nature and preparation for clinical use

Abstract

Bibliographical note

Access to Document

Other files and links

Fingerprint

Cite this