Clostridium botulinum toxins: Nature and preparation for clinical use

J. Melling*, P. Hambleton, Clifford Shone

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

94 Citations (Scopus)


C. botulinum neurotoxins are acutely toxic materials and act by inhibiting release of the neurotransmitter acetylcholine. The specific nature of this inhibition is discussed and the preparation and purification of Type A toxin specifically for clinical use is described.

Original languageEnglish
Pages (from-to)16-23
Number of pages8
JournalEye (Basingstoke)
Issue number1
Publication statusPublished - Jan 1988

Bibliographical note

Copyright 2016 Elsevier B.V., All rights reserved.


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