Cirrhosis and liver transplantation in patients co-infected with HIV and hepatitis B or C: an observational cohort study

On behalf of the Joint UK CHIC and liver transplant advisory group

doi:10.1007/s15010-016-0976-x

Cirrhosis and liver transplantation in patients co-infected with HIV and hepatitis B or C: an observational cohort study

On behalf of the Joint UK CHIC and liver transplant advisory group

Research output: Contribution to journal › Article › peer-review

5 Citations (Scopus)

Abstract

This study assessed the likelihood of referral for liver transplantation assessment in a prospective cohort of patients co-infected with HIV and hepatitis B or C with complications of cirrhosis. There were 141 co-infected patients from 11 UK centres with at least one complication of cirrhosis recorded (either decompensation or hepatocellular carcinoma) out of 772 identified with cirrhosis and/or HCC. Only 23 of these 141 (16.3%) were referred for liver transplantation assessment, even though referral is recommended for co-infected patients after the first decompensation episode.

Original language	English
Pages (from-to)	215-220
Number of pages	6
Journal	Infection
Volume	45
Issue number	2
DOIs	https://doi.org/10.1007/s15010-016-0976-x
Publication status	Published - 1 Apr 2017
Externally published	Yes

Bibliographical note

Funding Information:
This work received no specific funding. The UK-CHIC study is funded by the Medical Research Council UK (Grant numbers: G0000199; G0600337; G0900274). CWG holds an NIHR Clinical Lectureship.

Publisher Copyright:
© 2017, The Author(s).

Keywords

Cirrhosis
Co-infection
Hepatitis B
Hepatitis C
HIV
Liver transplantation

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1007/s15010-016-0976-x

Cite this

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title = "Cirrhosis and liver transplantation in patients co-infected with HIV and hepatitis B or C: an observational cohort study",

abstract = "This study assessed the likelihood of referral for liver transplantation assessment in a prospective cohort of patients co-infected with HIV and hepatitis B or C with complications of cirrhosis. There were 141 co-infected patients from 11 UK centres with at least one complication of cirrhosis recorded (either decompensation or hepatocellular carcinoma) out of 772 identified with cirrhosis and/or HCC. Only 23 of these 141 (16.3%) were referred for liver transplantation assessment, even though referral is recommended for co-infected patients after the first decompensation episode.",

keywords = "Cirrhosis, Co-infection, Hepatitis B, Hepatitis C, HIV, Liver transplantation",

author = "{On behalf of the Joint UK CHIC and liver transplant advisory group} and Charlotte Warren-Gash and Kate Childs and Alicia Thornton and Sanjay Bhagani and Shirin Demma and Ankur Srivastava and Clifford Leen and Kosh Agarwal and Rodger, {Alison J.} and Sabin, {Caroline A.}",

note = "Funding Information: This work received no specific funding. The UK-CHIC study is funded by the Medical Research Council UK (Grant numbers: G0000199; G0600337; G0900274). CWG holds an NIHR Clinical Lectureship. Publisher Copyright: {\textcopyright} 2017, The Author(s).",

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doi = "10.1007/s15010-016-0976-x",

language = "English",

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T1 - Cirrhosis and liver transplantation in patients co-infected with HIV and hepatitis B or C

T2 - an observational cohort study

AU - On behalf of the Joint UK CHIC and liver transplant advisory group

AU - Warren-Gash, Charlotte

AU - Childs, Kate

AU - Thornton, Alicia

AU - Bhagani, Sanjay

AU - Demma, Shirin

AU - Srivastava, Ankur

AU - Leen, Clifford

AU - Agarwal, Kosh

AU - Rodger, Alison J.

AU - Sabin, Caroline A.

N1 - Funding Information: This work received no specific funding. The UK-CHIC study is funded by the Medical Research Council UK (Grant numbers: G0000199; G0600337; G0900274). CWG holds an NIHR Clinical Lectureship. Publisher Copyright: © 2017, The Author(s).

PY - 2017/4/1

Y1 - 2017/4/1

N2 - This study assessed the likelihood of referral for liver transplantation assessment in a prospective cohort of patients co-infected with HIV and hepatitis B or C with complications of cirrhosis. There were 141 co-infected patients from 11 UK centres with at least one complication of cirrhosis recorded (either decompensation or hepatocellular carcinoma) out of 772 identified with cirrhosis and/or HCC. Only 23 of these 141 (16.3%) were referred for liver transplantation assessment, even though referral is recommended for co-infected patients after the first decompensation episode.

AB - This study assessed the likelihood of referral for liver transplantation assessment in a prospective cohort of patients co-infected with HIV and hepatitis B or C with complications of cirrhosis. There were 141 co-infected patients from 11 UK centres with at least one complication of cirrhosis recorded (either decompensation or hepatocellular carcinoma) out of 772 identified with cirrhosis and/or HCC. Only 23 of these 141 (16.3%) were referred for liver transplantation assessment, even though referral is recommended for co-infected patients after the first decompensation episode.

KW - Cirrhosis

KW - Co-infection

KW - Hepatitis B

KW - Hepatitis C

KW - HIV

KW - Liver transplantation

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AN - SCOPUS:85008155488

VL - 45

SP - 215

EP - 220

JO - Infection

JF - Infection

SN - 0300-8126

IS - 2

ER -

Cirrhosis and liver transplantation in patients co-infected with HIV and hepatitis B or C: an observational cohort study

Abstract

Bibliographical note

Keywords

UN SDGs

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