Chronic excretion of a norovirus in a child with cartilage hair hypoplasia (CHH)

Christopher Gallimore; David Lewis; Clive Taylor; Andrew Cant; Andrew Gennery; Jim J. Gray

doi:10.1016/j.jcv.2003.10.007

Chronic excretion of a norovirus in a child with cartilage hair hypoplasia (CHH)

Christopher Gallimore^*, David Lewis, Clive Taylor, Andrew Cant, Andrew Gennery, Jim J. Gray

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

68 Citations (Scopus)

Abstract

We have demonstrated the long-term excretion of a stable recombinant norovirus in a patient with cartilage hair hypoplasia (CHH), with a T cell immunodeficiency, following bone marrow transplantation (BMT). The patient excreted an ARG320/1999/US-like recombinant norovirus (rGII-3) for 156 days during a period of immune reconstitution. The child was symptomatic during the period of virus shedding. It is not known if the child acquired the recombinant strain or if recombination occurred in vivo.

Original language	English
Pages (from-to)	196-204
Number of pages	9
Journal	Journal of Clinical Virology
Volume	30
Issue number	2
DOIs	https://doi.org/10.1016/j.jcv.2003.10.007
Publication status	Published - Jun 2004

Keywords

BMT
CHH
Norovirus
Recombinant
T cell immunodeficiency

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1016/j.jcv.2003.10.007

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abstract = "We have demonstrated the long-term excretion of a stable recombinant norovirus in a patient with cartilage hair hypoplasia (CHH), with a T cell immunodeficiency, following bone marrow transplantation (BMT). The patient excreted an ARG320/1999/US-like recombinant norovirus (rGII-3) for 156 days during a period of immune reconstitution. The child was symptomatic during the period of virus shedding. It is not known if the child acquired the recombinant strain or if recombination occurred in vivo.",

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author = "Christopher Gallimore and David Lewis and Clive Taylor and Andrew Cant and Andrew Gennery and Gray, {Jim J.}",

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T1 - Chronic excretion of a norovirus in a child with cartilage hair hypoplasia (CHH)

AU - Gallimore, Christopher

AU - Lewis, David

AU - Taylor, Clive

AU - Cant, Andrew

AU - Gennery, Andrew

AU - Gray, Jim J.

PY - 2004/6

Y1 - 2004/6

N2 - We have demonstrated the long-term excretion of a stable recombinant norovirus in a patient with cartilage hair hypoplasia (CHH), with a T cell immunodeficiency, following bone marrow transplantation (BMT). The patient excreted an ARG320/1999/US-like recombinant norovirus (rGII-3) for 156 days during a period of immune reconstitution. The child was symptomatic during the period of virus shedding. It is not known if the child acquired the recombinant strain or if recombination occurred in vivo.

AB - We have demonstrated the long-term excretion of a stable recombinant norovirus in a patient with cartilage hair hypoplasia (CHH), with a T cell immunodeficiency, following bone marrow transplantation (BMT). The patient excreted an ARG320/1999/US-like recombinant norovirus (rGII-3) for 156 days during a period of immune reconstitution. The child was symptomatic during the period of virus shedding. It is not known if the child acquired the recombinant strain or if recombination occurred in vivo.

KW - BMT

KW - CHH

KW - Norovirus

KW - Recombinant

KW - T cell immunodeficiency

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JO - Journal of Clinical Virology

JF - Journal of Clinical Virology

SN - 1386-6532

IS - 2

ER -

Chronic excretion of a norovirus in a child with cartilage hair hypoplasia (CHH)

Abstract

Keywords

UN SDGs

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