TY - JOUR
T1 - Changes in the use of anti-asthmatic medication in an international cohort
AU - Janson, Christer
AU - de Marco, R.
AU - Accordini, S.
AU - Almar, E.
AU - Bugiani, M.
AU - Carolei, A.
AU - Cazzoletti, L.
AU - Cerveri, I.
AU - Corsico, A.
AU - Duran-Tauleria, E.
AU - Gislason, D.
AU - Gulsvik, A.
AU - Jõgi, R.
AU - Marinoni, A.
AU - Martínez-Moratalla, J.
AU - Pin, I.
AU - Vermeire, P.
AU - Jarvis, D.
PY - 2005/12
Y1 - 2005/12
N2 - The aim of this study was to describe changes in pharmacotherapy for asthma since the early 1990s in an international cohort of young and middle-aged adults. A total of 28 centres from 14 countries participated in a longitudinal study. The study included 8,829 subjects with a mean follow-up time of 8.7 yrs. Change in the prevalence of use for medication was expressed as absolute net change (95% confidence interval) standardised to a 10-yr period. The use of anti-asthmatics was found to have increased by 3.1% (2.4-3.7%) and the prevalence of symptomatic asthma by 4.0% (3.5-4.5%). In the sample with asthma in both surveys (n=423), the use of inhaled corticosteroids increased by 12.2% (6.6-17.8%). Despite this, only 17.2% were using inhaled corticosteroids on a daily basis at follow-up. Females with continuous asthma were more likely, compared with males, and smokers with asthma, to have started using inhaled corticosterolds since the first survey. The use of anti-asthmatics has increased in a pattern consistent with current consensus on treatment. However, despite increased use of inhaled corticosterolds, a large majority of subjects with symptomatic asthma do not use this treatment on a daily basis, particularly males and smokers with asthma. Copyright
AB - The aim of this study was to describe changes in pharmacotherapy for asthma since the early 1990s in an international cohort of young and middle-aged adults. A total of 28 centres from 14 countries participated in a longitudinal study. The study included 8,829 subjects with a mean follow-up time of 8.7 yrs. Change in the prevalence of use for medication was expressed as absolute net change (95% confidence interval) standardised to a 10-yr period. The use of anti-asthmatics was found to have increased by 3.1% (2.4-3.7%) and the prevalence of symptomatic asthma by 4.0% (3.5-4.5%). In the sample with asthma in both surveys (n=423), the use of inhaled corticosteroids increased by 12.2% (6.6-17.8%). Despite this, only 17.2% were using inhaled corticosteroids on a daily basis at follow-up. Females with continuous asthma were more likely, compared with males, and smokers with asthma, to have started using inhaled corticosterolds since the first survey. The use of anti-asthmatics has increased in a pattern consistent with current consensus on treatment. However, despite increased use of inhaled corticosterolds, a large majority of subjects with symptomatic asthma do not use this treatment on a daily basis, particularly males and smokers with asthma. Copyright
KW - Asthma
KW - Epidemiology
KW - Inhaled corticosteroids
KW - Smoking
KW - Therapy
UR - http://www.scopus.com/inward/record.url?scp=29244471723&partnerID=8YFLogxK
U2 - 10.1183/09031936.05.00031905
DO - 10.1183/09031936.05.00031905
M3 - Article
C2 - 16319334
AN - SCOPUS:29244471723
SN - 0903-1936
VL - 26
SP - 1047
EP - 1055
JO - European Respiratory Journal
JF - European Respiratory Journal
IS - 6
ER -