Attempts to immunize monkeys against experimental infection with Herpesvirus suis

A. Baskerville*, Graham Lloyd

*Corresponding author for this work

    Research output: Contribution to journalArticlepeer-review

    1 Citation (Scopus)

    Abstract

    Attempts were made to immunize grivet monkeys by intranasal administration of 2 doses of the avirulent Bartha strain of Aujeszky's disease virus (ADV). They were later challenged by the same route with virulent ADV. Vaccination failed to provide any protection and all the animals died of encephalomyelitis 9 to 14 days after infection. The clinical disease was more prolonged than in non-immunized monkeys, but the nature of the histological lesions and their distribution in the brain were the same.

    Original languageEnglish
    Pages (from-to)591-596
    Number of pages6
    JournalJournal of Comparative Pathology
    Volume87
    Issue number4
    DOIs
    Publication statusPublished - Oct 1977

    Fingerprint

    Dive into the research topics of 'Attempts to immunize monkeys against experimental infection with Herpesvirus suis'. Together they form a unique fingerprint.

    Cite this