TY - JOUR
T1 - Assessment of blood lead levels in 2–7 year-old children in Poti, Georgia, 2023
T2 - A pilot study of environmental lead exposure sources
AU - Bainduri, Milena
AU - Crabbe, Helen
AU - Marczylo, Tim
AU - Mondal, Debapriya
AU - Saei, Ayoub
AU - Akhalaia, Khatuna
AU - Sargsyan, Aelita
AU - Khonelidze, Irma
AU - Tsiklauri, Robinzon
AU - Laycock, Adam
AU - Jankhoteli, Tamar
AU - Ruadze, Ekaterine
N1 - Publisher Copyright:
© 2025
PY - 2025/8/1
Y1 - 2025/8/1
N2 - Lead exposure remains a significant public health concern, particularly for children. This pilot study assessed changes in blood lead levels (BLL) among 2–7-year-old children in Poti, Georgia, between 2018 and 2023. The study aimed to evaluate BLL trends and identify potential environmental sources of lead exposure. Venous blood samples from 63 children were analyzed, and environmental samples—including dust, soil, paint, spices, sugar, and salt—were collected from 50 households. The geometric mean BLL decreased significantly from 7.5 μg/dL (2018) to 2.05 μg/dL (2023). Despite this decline, 20.6 % of children had BLLs above the U.S. reference level of 3.5 μg/dL, highlighting continued exposure risks. Among environmental samples, lead concentrations exceeded reference values in 66.7 % of paint, 43.9 % of soil, and 14.3 % of dust samples. Spice lead concentrations showed a marked decline, with a geometric mean of 4.2 mg/kg in 2018 and 0.25 mg/kg in 2023. This study demonstrates significant progress in reducing lead exposure in children, likely attributable to recent public health initiatives. However, persistent environmental lead sources, particularly in dust and soil necessitate sustained efforts to mitigate exposure. Further nationwide studies are essential to monitor trends, identify hotspots and inform targeted interventions.
AB - Lead exposure remains a significant public health concern, particularly for children. This pilot study assessed changes in blood lead levels (BLL) among 2–7-year-old children in Poti, Georgia, between 2018 and 2023. The study aimed to evaluate BLL trends and identify potential environmental sources of lead exposure. Venous blood samples from 63 children were analyzed, and environmental samples—including dust, soil, paint, spices, sugar, and salt—were collected from 50 households. The geometric mean BLL decreased significantly from 7.5 μg/dL (2018) to 2.05 μg/dL (2023). Despite this decline, 20.6 % of children had BLLs above the U.S. reference level of 3.5 μg/dL, highlighting continued exposure risks. Among environmental samples, lead concentrations exceeded reference values in 66.7 % of paint, 43.9 % of soil, and 14.3 % of dust samples. Spice lead concentrations showed a marked decline, with a geometric mean of 4.2 mg/kg in 2018 and 0.25 mg/kg in 2023. This study demonstrates significant progress in reducing lead exposure in children, likely attributable to recent public health initiatives. However, persistent environmental lead sources, particularly in dust and soil necessitate sustained efforts to mitigate exposure. Further nationwide studies are essential to monitor trends, identify hotspots and inform targeted interventions.
KW - Blood lead level (BLL)
KW - Children
KW - Contamination
KW - Environmental sampling
KW - Exposure
KW - Georgia
KW - Lead (Pb)
UR - http://www.scopus.com/inward/record.url?scp=105004037362&partnerID=8YFLogxK
U2 - 10.1016/j.envres.2025.121708
DO - 10.1016/j.envres.2025.121708
M3 - Article
C2 - 40288736
AN - SCOPUS:105004037362
SN - 0013-9351
VL - 278
JO - Environmental Research
JF - Environmental Research
M1 - 121708
ER -