TY - JOUR
T1 - Analysis of recombination in Campylobacter jejuni from MLST population data
AU - Fearnhead, Paul
AU - Smith, Nick G.C.
AU - Barrigas, Mishele
AU - Fox, Andrew
AU - French, Nigel
PY - 2005/9
Y1 - 2005/9
N2 - We analyze recombination in C. jejuni using MLST data from isolates taken from wild birds, cattle, wild rabbits, and water in a 100-km2 study region in Cheshire, UK. We use a recent approximate likelihood method for inference, based on combining likelihood information from all pairs of segregating (polymorphic) sites in the data. We find substantial evidence for recombination, but only for recombination with short tract lengths, of around 225-750 bp. We estimate that the rate of recombination is of a similar magnitude to the rate of mutation.
AB - We analyze recombination in C. jejuni using MLST data from isolates taken from wild birds, cattle, wild rabbits, and water in a 100-km2 study region in Cheshire, UK. We use a recent approximate likelihood method for inference, based on combining likelihood information from all pairs of segregating (polymorphic) sites in the data. We find substantial evidence for recombination, but only for recombination with short tract lengths, of around 225-750 bp. We estimate that the rate of recombination is of a similar magnitude to the rate of mutation.
KW - Bacteria
KW - Campylobacter
KW - Helicobacter
KW - MLST
KW - Recombination rate
KW - Recombination tract length
UR - http://www.scopus.com/inward/record.url?scp=25144485341&partnerID=8YFLogxK
U2 - 10.1007/s00239-004-0316-0
DO - 10.1007/s00239-004-0316-0
M3 - Article
C2 - 16044246
AN - SCOPUS:25144485341
VL - 61
SP - 333
EP - 340
JO - Journal of Molecular Evolution
JF - Journal of Molecular Evolution
SN - 0022-2844
IS - 3
ER -