Advances in the development of vaccines against Neisseria meningitidis

Lionel K.K. Tan, George M. Carlone, Raymond Borrow*

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

188 Citations (Scopus)


Neisseria meningitidis remains a leading cause of meningitis and sepsis. This review provides an update on our understanding of immunity against meningococcal infection. Knowledge of the meningococcal genome has led to identification of novel antigens. A major challenge is to improve the immunogenicity of vaccines in infants, who are especially vulnerable to this infection.

Original languageEnglish
Pages (from-to)1511
Number of pages1
JournalNew England Journal of Medicine
Issue number16
Publication statusPublished - 22 Apr 2010


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