Accelerating progress towards tuberculosis elimination: The need for combination treatment and prevention

A. Reid; A. D. Grant; R. G. White; C. Dye; Emilia Vynnycky; K. Fielding; G. Churchyard; Y. Pillay

doi:10.5588/ijtld.14.0078

Accelerating progress towards tuberculosis elimination: The need for combination treatment and prevention

A. Reid^*, A. D. Grant, R. G. White, C. Dye, Emilia Vynnycky, K. Fielding, G. Churchyard, Y. Pillay

^*Corresponding author for this work

Modelling Economics Unit

Research output: Contribution to journal › Review article › peer-review

21 Citations (Scopus)

Abstract

Although estimated tuberculosis (TB) incidence is now falling globally, we are unlikely to achieve the Millennium Development Goal (MDG) TB targets without changing the emphasis of the global TB response in high human immunodeficiency virus prevalence settings. Two independent modelling exercises using South African data with different structures and assumptions conclude that, until new drugs, diagnostics and vaccines are available, a fully funded and accessible combination approach to anti-tuberculosis treatment and prevention, based on knowledge of local TB epidemiology and evidence-informed policy, is essential to accelerate progress towards zero new tuberculous infections, zero TB deaths and zero suffering from TB.

Original language	English
Pages (from-to)	5-9
Number of pages	5
Journal	International Journal of Tuberculosis and Lung Disease
Volume	19
Issue number	1
DOIs	https://doi.org/10.5588/ijtld.14.0078
Publication status	Published - 1 Jan 2015

Bibliographical note

Publisher Copyright:
© 2015 The Union.

Keywords

Modelling
Policy
Tuberculosis

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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title = "Accelerating progress towards tuberculosis elimination: The need for combination treatment and prevention",

abstract = "Although estimated tuberculosis (TB) incidence is now falling globally, we are unlikely to achieve the Millennium Development Goal (MDG) TB targets without changing the emphasis of the global TB response in high human immunodeficiency virus prevalence settings. Two independent modelling exercises using South African data with different structures and assumptions conclude that, until new drugs, diagnostics and vaccines are available, a fully funded and accessible combination approach to anti-tuberculosis treatment and prevention, based on knowledge of local TB epidemiology and evidence-informed policy, is essential to accelerate progress towards zero new tuberculous infections, zero TB deaths and zero suffering from TB.",

keywords = "Modelling, Policy, Tuberculosis",

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T1 - Accelerating progress towards tuberculosis elimination

T2 - The need for combination treatment and prevention

AU - Reid, A.

AU - Grant, A. D.

AU - White, R. G.

AU - Dye, C.

AU - Vynnycky, Emilia

AU - Fielding, K.

AU - Churchyard, G.

AU - Pillay, Y.

PY - 2015/1/1

Y1 - 2015/1/1

N2 - Although estimated tuberculosis (TB) incidence is now falling globally, we are unlikely to achieve the Millennium Development Goal (MDG) TB targets without changing the emphasis of the global TB response in high human immunodeficiency virus prevalence settings. Two independent modelling exercises using South African data with different structures and assumptions conclude that, until new drugs, diagnostics and vaccines are available, a fully funded and accessible combination approach to anti-tuberculosis treatment and prevention, based on knowledge of local TB epidemiology and evidence-informed policy, is essential to accelerate progress towards zero new tuberculous infections, zero TB deaths and zero suffering from TB.

AB - Although estimated tuberculosis (TB) incidence is now falling globally, we are unlikely to achieve the Millennium Development Goal (MDG) TB targets without changing the emphasis of the global TB response in high human immunodeficiency virus prevalence settings. Two independent modelling exercises using South African data with different structures and assumptions conclude that, until new drugs, diagnostics and vaccines are available, a fully funded and accessible combination approach to anti-tuberculosis treatment and prevention, based on knowledge of local TB epidemiology and evidence-informed policy, is essential to accelerate progress towards zero new tuberculous infections, zero TB deaths and zero suffering from TB.

KW - Modelling

KW - Policy

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AN - SCOPUS:84918772496

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IS - 1

ER -

Accelerating progress towards tuberculosis elimination: The need for combination treatment and prevention

Abstract

Bibliographical note

Keywords

UN SDGs

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