TY - JOUR
T1 - A microcomputer based system for quantifying the spatial distribution of inhaled particles in histological lung sections
AU - Birchall, A.
AU - Hodgson, Alan
N1 - Copyright:
Copyright 2007 Elsevier B.V., All rights reserved.
PY - 1984
Y1 - 1984
N2 - A system is described for quantifying the spatial distribution of inhaled particles in complete lobar histological sections of rodent lung. It is based on a semiautomatic image analyser, linked to a readily available microcomputer. Application of the system to quantify the aggregation of particles, and their distances from airways and lung periphery is described. The observed distributions are compared with the expected distributions from a random set of particles, and the significance of the difference is calculated. Each statistical test is illustrated by an example.
AB - A system is described for quantifying the spatial distribution of inhaled particles in complete lobar histological sections of rodent lung. It is based on a semiautomatic image analyser, linked to a readily available microcomputer. Application of the system to quantify the aggregation of particles, and their distances from airways and lung periphery is described. The observed distributions are compared with the expected distributions from a random set of particles, and the significance of the difference is calculated. Each statistical test is illustrated by an example.
UR - http://www.scopus.com/inward/record.url?scp=0021178889&partnerID=8YFLogxK
U2 - 10.1088/0031-9155/29/1/004
DO - 10.1088/0031-9155/29/1/004
M3 - Article
C2 - 6701191
AN - SCOPUS:0021178889
SN - 0031-9155
VL - 29
SP - 31
EP - 43
JO - Physics in Medicine and Biology
JF - Physics in Medicine and Biology
IS - 1
M1 - 004
ER -