A case-case comparison of Campylobacter coli and Campylobacter jejuni infection: A tool for generating hypotheses

Iain A. Gillespie, Sarah J. O'Brien*, Jennifer A. Frost, Goutam Adak, Peter Horby, Anthony V. Swan, Michael J. Painter, Keith R. Neal

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

243 Citations (Scopus)

Abstract

Preventing campylobacteriosis depends on a thorough understanding of its epidemiology. We used case-case analysis to compare cases of Campylobacter coli infection with cases of C. jejuni infection, to generate hypotheses for infection from standardized, population-based sentinel surveillance information in England and Wales. Persons with C. coli infection were more likely to have drunk bottled water than were those with C. jejuni infection and, in general, were more likely to have eaten pâté. Important differences in exposures were identified for these two Campylobacter species. Exposures that are a risk for infection for both comparison groups might not be identified or might be underestimated by case-case analysis. Similarly, the magnitude or direction of population risk cannot be assessed accurately. Nevertheless, our findings suggest that case-control studies should be conducted at the species level.

Original languageEnglish
Pages (from-to)937-942
Number of pages6
JournalEmerging Infectious Diseases
Volume8
Issue number9
DOIs
Publication statusPublished - Sep 2002

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